1997
T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration.
Romanic A, Graesser D, Baron J, Visintin I, Janeway C, Madri J. T cell adhesion to endothelial cells and extracellular matrix is modulated upon transendothelial cell migration. Laboratory Investigation 1997, 76: 11-23. PMID: 9010446.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainCell AdhesionCell MovementCells, CulturedCollagenEncephalomyelitis, Autoimmune, ExperimentalEndothelium, VascularExtracellular MatrixFibronectinsFlow CytometryIntegrin alpha4beta1IntegrinsIntercellular Adhesion Molecule-1Interleukin-2Lymphocyte Function-Associated Antigen-1MiceMice, Inbred StrainsMyelin Basic ProteinPeptide FragmentsReceptors, Lymphocyte HomingReceptors, Very Late AntigenRecombinant ProteinsT-LymphocytesUp-RegulationVascular Cell Adhesion Molecule-1ConceptsAdhesion molecule-1T cellsMolecule-1Recombinant vascular cell adhesion molecule-1Recombinant intercellular adhesion molecule-1Experimental autoimmune encephalomyelitis (EAE) miceLate activation antigen-4Vascular cell adhesion molecule-1Intercellular adhesion molecule-1Cell adhesion molecule-1T cell migrationExtracellular matrixCell migrationTransendothelial cell migrationAntigen-4Integrin surface expressionInflammatory responseCD4 expressionBrain sectionsT cell adhesionPerivascular tissueEndothelial cellsIntegrin expressionCell-ECM interactionsSurface expression
1996
The roles of adhesion molecules and proteinases in lymphocyte transendothelial migration
Madri J, Graesser D, Haas T. The roles of adhesion molecules and proteinases in lymphocyte transendothelial migration. Biochemistry And Cell Biology 1996, 74: 749-757. PMID: 9164645, DOI: 10.1139/o96-082.Peer-Reviewed Original Research
1995
Human capillary endothelial cells from abdominal wall adipose tissue: Isolation using an anti-pecam antibody
Springhorn J, Madri J, Squinto S. Human capillary endothelial cells from abdominal wall adipose tissue: Isolation using an anti-pecam antibody. In Vitro Cellular & Developmental Biology - Animal 1995, 31: 473-481. PMID: 8589892, DOI: 10.1007/bf02634261.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAdipose TissueAnimalsAntibodies, MonoclonalAntigens, Differentiation, MyelomonocyticCell Adhesion MoleculesCell SeparationCell Transformation, ViralCells, CulturedEndothelium, VascularGrowth HormoneHumansLectinsPlant LectinsPlatelet Endothelial Cell Adhesion Molecule-1Vascular Cell Adhesion Molecule-1Von Willebrand FactorConceptsCapillary endothelial cellsHuman capillary endothelial cellsAnti-PECAM antibodyEndothelial cellsCellular adhesion moleculesVon Willebrand factorAdipose tissueDensity lipoproteinAdhesion molecule antibodyGrowth hormoneFlow cytometryMolecule antibodiesAdhesion moleculesAntibodiesWillebrand factorPassage sixNormal patternAntibody methodCell isolatesImmunofluorescent labelingAgglutinin lectinType I
1994
The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent.
Romanic A, Madri J. The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. Journal Of Cell Biology 1994, 125: 1165-1178. PMID: 7515069, PMCID: PMC2120055, DOI: 10.1083/jcb.125.5.1165.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Recombinant VCAM-1T cellsT cell transmigrationEndothelial cellsNegative endothelial cellsCell transmigrationCell adhesion molecule-1Transmigrated T cellsExperimental autoimmune encephalomyelitisT cell extravasationAdhesion molecule-1Late antigen-4VCAM-1 positive cellsMyelin basic proteinAutoimmune encephalomyelitisEndothelial cell monolayersAntigen-4Brain parenchymaNormal miceEndothelial cell layerPositive cellsMolecule-1Perivascular tissueT cell adhesion
1993
Differential induction of VCAM-1 on human iliac venous and arterial endothelial cells and its role in adhesion.
Hauser I, Johnson D, Madri J. Differential induction of VCAM-1 on human iliac venous and arterial endothelial cells and its role in adhesion. The Journal Of Immunology 1993, 151: 5172-85. PMID: 7693806, DOI: 10.4049/jimmunol.151.10.5172.Peer-Reviewed Original ResearchMeSH KeywordsAdultCell AdhesionCell Adhesion MoleculesCells, CulturedE-SelectinEndothelium, VascularFemaleHumansIliac ArteryIliac VeinIntercellular Adhesion Molecule-1Lymphocyte Function-Associated Antigen-1Middle AgedReceptors, Very Late AntigenRNA, MessengerTetradecanoylphorbol AcetateTumor Necrosis Factor-alphaVascular Cell Adhesion Molecule-1ConceptsArterial endothelial cellsICAM-1VCAM-1Venous endothelial cellsEndothelial cellsTNF-alphaU937 cell adhesionELAM-1VCAM-1 cell surface expressionTNF-alpha-induced VCAM-1 expressionAdhesion molecules VCAM-1ICAM-2U937 cellsAdhesion molecules ICAM-1TNF-alpha-induced expressionLate activation AgVCAM-1 expressionMolecules ICAM-1VCAM-1/VLAMonocyte-like cell line U937TNF-alpha treatmentVessel endothelial cellsAdhesion of PMALarge vessel endothelial cellsEC typesSurface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma.
Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA. Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchyma. Journal Of Experimental Medicine 1993, 177: 57-68. PMID: 7678116, PMCID: PMC2190872, DOI: 10.1084/jem.177.1.57.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalBrainCD4-Positive T-LymphocytesCell Adhesion MoleculesCell MovementClone CellsEncephalomyelitis, Autoimmune, ExperimentalIntercellular Adhesion Molecule-1MiceMice, Inbred BALB CMyelin Basic ProteinReceptors, Very Late AntigenVascular Cell Adhesion Molecule-1ConceptsAlpha 4 integrinsExperimental autoimmune encephalomyelitisAdhesion molecule-1T cellsBrain parenchymaT cell linesEncephalitogenic clonesAlpha 4Surface expressionMolecule-1Recombinant vascular cell adhesion molecule-1T helper type 1 clonesCD4 T cell linesCloned T cell linesTh1 cytokine interleukin-2Vascular cell adhesion molecule-1Intercellular adhesion molecule-1Cell adhesion molecule-1Tumor necrosis factor betaTh1 T cellsEffector T cellsCD4 T cellsMajor pathogenic factorT cell entryNecrosis factor beta