2015
Cell–extracellular matrix interactions in oral tumorigenesis: Roles of podoplanin and CD44 and modulation of Hippo pathway
Tsuneki M, Madri J, Saku T. Cell–extracellular matrix interactions in oral tumorigenesis: Roles of podoplanin and CD44 and modulation of Hippo pathway. Journal Of Oral Biosciences 2015, 57: 45-53. DOI: 10.1016/j.job.2015.02.004.Peer-Reviewed Original ResearchCell-extracellular matrix interactionsHippo pathwayExtracellular matrixDynamic reciprocal interactionsMatrix interactionsCell surfaceHyaluronan-rich extracellular matrixMultifunctional transmembrane proteinBasolateral cell surfaceVascular endothelialEndothelial cell survivalAdhesion moleculesStromal cellsVascular endothelial cell survivalTransmembrane proteinMurine hemangioendothelioma cellsTumor cellsSquamous cell carcinoma cellsOral squamous cell carcinoma cellsCell survivalContact inhibitionVE-cadherinTissue architectureTumor survivalIntercellular spaces
2014
Adhesion Molecule-Mediated Hippo Pathway Modulates Hemangioendothelioma Cell Behavior
Tsuneki M, Madri JA. Adhesion Molecule-Mediated Hippo Pathway Modulates Hemangioendothelioma Cell Behavior. Molecular And Cellular Biology 2014, 34: 4485-4499. PMID: 25266662, PMCID: PMC4248725, DOI: 10.1128/mcb.00671-14.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, CDApoptosisBrainCadherinsCaspase 3Cell Line, TumorCell ProliferationHemangioendotheliomaHippo Signaling PathwayImidazolesInhibitor of Apoptosis ProteinsLIM Domain ProteinsMiceMice, Inbred C57BLNaphthoquinonesPlatelet Endothelial Cell Adhesion Molecule-1Protein Serine-Threonine KinasesRepressor ProteinsRNA, Small InterferingSignal TransductionSurvivinConceptsHippo pathwayCell adhesion moleculeAjuba expressionCell proliferationAdhesion moleculesSmall interference RNA transfectionEffector caspase-3Murine hemangioendothelioma cellsPromoter interactionsApoptotic mechanismsMolecule modulationCell behaviorContact inhibitionEndothelial cell proliferationRNA transfectionVE-cadherinCaspase-3Microvascular endothelial cell proliferationApoptosisHemangioendothelioma cellsPathwayCell culturesProliferationEndothelial cell adhesion moleculesExpression