1992
Indomethacin promotes germinal matrix microvessel maturation in the newborn beagle pup.
Ment L, Stewart W, Ardito T, Huang E, Madri J. Indomethacin promotes germinal matrix microvessel maturation in the newborn beagle pup. Stroke 1992, 23: 1132-1137. PMID: 1636188, DOI: 10.1161/01.str.23.8.1132.Peer-Reviewed Original ResearchConceptsNewborn beagle pupsPostnatal day 2Germinal matrixPostnatal ageBeagle pupsIntraventricular hemorrhageVessel densityDay 2Postnatal day 1Laminin depositionMechanism of actionMicrovessel maturationStudy medicationBeta 1 integrinImmunohistochemical studyPostnatal dayDose i.Animal studiesDay 1IndomethacinNewborn pupsHemorrhageBasement membrane depositionBuffered formalinCollagen staining
1989
Effect of platelet factors on migration of cultured bovine aortic endothelial and smooth muscle cells.
Bell L, Madri J. Effect of platelet factors on migration of cultured bovine aortic endothelial and smooth muscle cells. Circulation Research 1989, 65: 1057-1065. PMID: 2791219, DOI: 10.1161/01.res.65.4.1057.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsPlatelet-derived growth factorSMC proliferationPlatelet factorEC proliferationMuscle cellsGrowth factorEndothelial cell injuryMechanism of actionVascular injuryVascular diseaseCell injurySMC migrationBovine aortic ECsAortic ECsInjuryNorepinephrineProliferationHistaminePresent studyResponse of ECPhenoxybenzamineKetanserinCellsAtherosclerosis