2015
ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy
Albright RA, Stabach P, Cao W, Kavanagh D, Mullen I, Braddock AA, Covo MS, Tehan M, Yang G, Cheng Z, Bouchard K, Yu ZX, Thorn S, Wang X, Folta-Stogniew EJ, Negrete A, Sinusas AJ, Shiloach J, Zubal G, Madri JA, De La Cruz EM, Braddock DT. ENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancy. Nature Communications 2015, 6: 10006. PMID: 26624227, PMCID: PMC4686714, DOI: 10.1038/ncomms10006.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseVascular calcificationArterial calcificationOrphan diseaseCommon diseaseSequelae of diseaseEctopic vascular calcificationInternal elastic laminaPrevent mortalityRenal failureCardiac failureKidney diseaseSubcutaneous administrationRodent modelsAnimal modelsEctopic calcificationVascular wallLarge arteriesElastic laminaDiseaseCalcificationCalciphylaxisDecreased concentrationSclerosisArtery
2009
Modeling the neurovascular niche: implications for recovery from CNS injury.
Madri JA. Modeling the neurovascular niche: implications for recovery from CNS injury. Journal Of Physiology And Pharmacology 2009, 60 Suppl 4: 95-104. PMID: 20083857.Peer-Reviewed Original ResearchConceptsNeurovascular nicheCNS injuryHIF-1alphaSpinal cord injuryNeural stem cell survivalNeurogenic zonesCord injuryTraumatic brainMurine modelSDF-1Sublethal hypoxiaInjuryStem cell survivalNRP-1Neurodegenerative diseasesEndothelial cellsHypoxiaExpression levelsSurvivalCell survivalFocused reviewDiseaseVariable responseTrkBBDNF
2007
Juvenile Hyaline Fibromatosis and Infantile Systemic Hyalinosis Overlap Associated With a Novel Mutation in Capillary Morphogenesis Protein-2 Gene
Antaya RJ, Cajaiba MM, Madri J, Lopez MA, Ramirez MC, Martignetti JA, Reyes-Múgica M. Juvenile Hyaline Fibromatosis and Infantile Systemic Hyalinosis Overlap Associated With a Novel Mutation in Capillary Morphogenesis Protein-2 Gene. American Journal Of Dermatopathology 2007, 29: 99-103. PMID: 17284973, DOI: 10.1097/01.dad.0000245636.39098.e5.Peer-Reviewed Original ResearchConceptsJuvenile hyaline fibromatosisInfantile systemic hyalinosisHyaline fibromatosisCapillary morphogenesis gene 2Painful skin lesionsImpairment of movementNovel mutationsVisceral involvementClinical pictureClinicopathologic findingsRare conditionSkin lesionsSystemic hyalinosisSubcutaneous tissueProtein 2 geneSevere disabilityGermline mutationsFibromatosisDiseaseAllelic diseasesGene 2Unclear natureMutationsHyalinosisLesions
1978
Gram-Negative Endocarditis Following Cystoscopy
Marier R, Valenti A, Madri J. Gram-Negative Endocarditis Following Cystoscopy. Journal Of Urology 1978, 119: 134-137. PMID: 340713, DOI: 10.1016/s0022-5347(17)57410-8.Peer-Reviewed Original ResearchConceptsMitral annulusHeart diseaseUrologic proceduresMitral valve infectionProphylactic antibiotic coverageUrinary tract infectionAmerican Heart AssociationAbsence of bacteriuriaCongenital heart diseaseMitral valve annulusValve infectionAntibiotic coverageInfectious complicationsUrinary retentionTract infectionsGram-negative endocarditisHeart AssociationRisk factorsValve annulusPatientsBacteriuriaCalcificationCystoscopyInfectionDisease