2023
Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures
Hsu J, Darden D, Du C, Marine J, Nichols S, Marcus G, Natale A, Noseworthy P, Selzman K, Varosy P, Masoudi F, Freeman J, Curtis J, Akar J, Kowey P. Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures. Journal Of The American College Of Cardiology 2023, 81: 867-878. PMID: 36858707, DOI: 10.1016/j.jacc.2022.11.060.Peer-Reviewed Original ResearchConceptsAtrial fibrillation ablation proceduresAblation RegistryHospital outcomesAblation proceduresSuccessful pulmonary vein isolationNational Cardiovascular Data RegistryOutcomes of patientsProspective cohort studyMajority of patientsPulmonary vein isolationEvidence-based guidelinesDifferent patient outcomesReal-world prevalenceProcedural admissionsHospital deathAF ablationCohort studyPericardial effusionVein isolationHeart failureLarge multicenterMajor complicationsCatheter ablationTreatment patternsPatient population
2022
Sex-based differences in atrial fibrillation ablation adverse events
Mszar R, Friedman D, Ong E, Du C, Wang Y, Zeitler E, Cunningham S, Akar J, Curtis J, Freeman J. Sex-based differences in atrial fibrillation ablation adverse events. Heart 2022, 109: 595-605. PMID: 36104219, DOI: 10.1136/heartjnl-2022-321192.Peer-Reviewed Original ResearchConceptsAcute pulmonary vein isolationAdverse eventsPulmonary vein isolationAtrial fibrillationHigh riskSex-based differencesVein isolationCatheter ablationFemale sexLarge prospective registryHospital adverse eventsMajor adverse eventsObservational cohort studyPhrenic nerve damageAF ablation proceduresQuality of lifeAblation RegistryMore comorbiditiesProspective registryAF ablationCohort studyPericardial effusionNerve damagePatient sexVascular injury
2020
Predictors of Cardiac Perforation With Catheter Ablation of Atrial Fibrillation
Friedman DJ, Pokorney SD, Ghanem A, Marcello S, Kalsekar I, Yadalam S, Akar JG, Freeman JV, Goldstein L, Khanna R, Piccini JP. Predictors of Cardiac Perforation With Catheter Ablation of Atrial Fibrillation. JACC Clinical Electrophysiology 2020, 6: 636-645. PMID: 32553212, DOI: 10.1016/j.jacep.2020.01.011.Peer-Reviewed Original ResearchConceptsPrevious cardiac surgeryCardiac perforationAF ablationIntracardiac echocardiographyCardiac surgeryFemale sexDiagnosis of hemopericardiumPatient risk factorsSubset of patientsAtrial fibrillation ablationContemporary clinical practiceIntraprocedural intracardiac echocardiographyLogistic regression modelsCardiac tamponadeFatal complicationProcedural complicationsRare complicationCatheter ablationFibrillation ablationAtrial fibrillationModifiable factorsRisk factorsProcedural safetyRisk scoreLower risk
2006
Idiopathic Epicardial Left Ventricular Tachycardia Originating Remote From the Sinus of Valsalva
Daniels DV, Lu YY, Morton JB, Santucci PA, Akar JG, Green A, Wilber DJ. Idiopathic Epicardial Left Ventricular Tachycardia Originating Remote From the Sinus of Valsalva. Circulation 2006, 113: 1659-1666. PMID: 16567566, DOI: 10.1161/circulationaha.105.611640.Peer-Reviewed Original ResearchConceptsIdiopathic ventricular tachycardiaMaximum deflection indexVentricular tachycardiaEpicardial ventricular tachycardiaDirect surgical ablationSinus of ValsalvaLeft ventricular epicardiumDeflection indexSite of originUnsuccessful ablationAortic sinusVenous mappingCatheter ablationOccasional patientSurgical ablationCoronary veinVT inductionTranspericardial approachVentricular sitesEndocardial activationEpicardial mappingPerivascular sitesECG patternVentricular endocardiumAnatomic constraints
2005
Incidence and determinants of left atrial scar in patients with paroxysmal and persistent atrial fibrillation undergoing catheter ablation
Lipman E, Madsen N, Lin A, Santucci P, Akar J, Anderson K, Dasari R, Joshi S, Gauri A, Wilber D. Incidence and determinants of left atrial scar in patients with paroxysmal and persistent atrial fibrillation undergoing catheter ablation. Heart Rhythm 2005, 2: s12. DOI: 10.1016/j.hrthm.2005.02.048.Peer-Reviewed Original ResearchSafety and efficacy of catheter ablation of repetitive monomorphic ventricular tachycardia arising from the sinus of Valsalva guided by intracardiac echocardiography
Lin A, Morton J, Joshi S, Dasari R, Gauri A, Lipman E, Santucci P, Akar J, Wilber D. Safety and efficacy of catheter ablation of repetitive monomorphic ventricular tachycardia arising from the sinus of Valsalva guided by intracardiac echocardiography. Heart Rhythm 2005, 2: s36. DOI: 10.1016/j.hrthm.2005.02.123.Peer-Reviewed Original Research
2003
Effect of Heating on Pulmonary Veins:
KOK LC, EVERETT TH, AKAR JG, HAINES DE. Effect of Heating on Pulmonary Veins:. Journal Of Cardiovascular Electrophysiology 2003, 14: 250-254. PMID: 12716105, DOI: 10.1046/j.1540-8167.2003.02490.x.Peer-Reviewed Original ResearchConceptsRadiofrequency energy catheter ablationHyperthermic exposurePulmonary vein stenosisChronic atrial fibrillationTreatment of patientsLoss of complianceHeat-induced contractionHeat exposurePV stenosisVein stenosisCatheter ablationAtrial fibrillationPulmonary veinsLeft atriumAcute effectsMain PVCanine heartPV specimensMean circumferenceDegrees CStenosisExposureBaselineCircumferenceCollagen matrix