Exploring Variation in Known Pharmacogenetic Variants and its Association with Drug Response in Different Mexican Populations
Gonzalez-Covarrubias V, Martínez-Magaña JJ, Coronado-Sosa R, Villegas-Torres B, Genis-Mendoza AD, Canales-Herrerias P, Nicolini H, Soberón X. Exploring Variation in Known Pharmacogenetic Variants and its Association with Drug Response in Different Mexican Populations. Pharmaceutical Research 2016, 33: 2644-2652. PMID: 27387170, DOI: 10.1007/s11095-016-1990-5.Peer-Reviewed Original ResearchConceptsGenetic variantsMajor continental groupsAllele frequency differencesSolute carrier gene familySignificant allele differencesDifferent Mexican populationsGene familyContinental groupsAllele differencesMexican MestizosAllele frequenciesRelevant targetsMore variationDifferent populationsDrug responseMexican populationPharmacogenetic variantsNative groupsVariantsPharmacogenetic targetsDifferent native groupsPopulationMicroarrayTransportersTarget