Featured Publications
Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence
Núñez-Rios DL, Martínez-Magaña JJ, Nagamatsu ST, Andrade-Brito DE, Forero DA, Orozco-Castaño CA, Montalvo-Ortiz JL. Central and Peripheral Immune Dysregulation in Posttraumatic Stress Disorder: Convergent Multi-Omics Evidence. Biomedicines 2022, 10: 1107. PMID: 35625844, PMCID: PMC9138536, DOI: 10.3390/biomedicines10051107.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPosttraumatic stress disorderPeripheral immune systemImmune systemInflammatory systemTrauma exposureStress disorderPeripheral immune dysregulationToll-like receptorsLifetime trauma exposurePotential novel drug targetsEtiology of PTSDImmune dysregulationInflammatory dysregulationHPA axisNovel drug targetsImmunological responseInflammatory signalingGeneral populationAnimal modelsIntegrative multi-omics approachPTSD treatmentMultifactorial disorderBrain tissueHallmark featureDysregulation
2023
W70. ASSOCIATION BETWEEN MBD5 GENE AND DEPRESSIVE SYMPTOMATOLOGY IN MEXICAN POPULATION: RESULTS FROM MXGDAR/ENCODAT COHORT
Camarena B, Sanabrais-Jiménez M, García A, Genis A, Villatoro-Velazquez J, Fleiz-Bautista C, Bustos-Gamiño M, Martínez-Magaña J, Nicolini H, Medina-Mora M. W70. ASSOCIATION BETWEEN MBD5 GENE AND DEPRESSIVE SYMPTOMATOLOGY IN MEXICAN POPULATION: RESULTS FROM MXGDAR/ENCODAT COHORT. European Neuropsychopharmacology 2023, 75: s141. DOI: 10.1016/j.euroneuro.2023.08.257.Peer-Reviewed Original ResearchDepressive symptomsAnxiety symptomsAnxiety disordersSubstantial disease burdenMexican populationGenetic principal componentsYears of lifeGeneralized anxiety disorderFindings of associationsDisease burdenHealthy controlsMexican cohortMajor depressiveGeneral populationDiagnostic criteriaLifetime symptomatologyGenetic overlapSymptomsMBD5 geneDepressiveBackground AnxietyCohortProtein 5DepressionGreater mortality
2021
Mental Health Problems Due to Social Isolation During the COVID-19 Pandemic in a Mexican Population
Genis-Mendoza A, Martínez-Magaña J, López-Narváez M, González-Castro T, Juárez-Rojop I, Nicolini H, Tovilla-Zárate C, Castillo-Avila R. Mental Health Problems Due to Social Isolation During the COVID-19 Pandemic in a Mexican Population. Frontiers In Public Health 2021, 9: 703450. PMID: 34888275, PMCID: PMC8649920, DOI: 10.3389/fpubh.2021.703450.Peer-Reviewed Original ResearchConceptsSymptoms of depressionDepressive symptomsSocial isolationPost-traumatic stressMexican populationSuicidal ideationCOVID-19 pandemicMental healthLow-calorie dietPersonal hygiene habitsYears of ageCOVID-19Cross-sectional online surveyMental health problemsHygiene habitsRisk factorsPsychiatric symptomsGeneral populationHealth problemsMental disordersSymptomsEating habitsPersonal hygieneDepressionPsychoactive substancesPsychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index
Ruiz-Ramos D, Martínez-Magaña JJ, García AR, Juarez-Rojop IE, Gonzalez-Castro TB, Tovilla-Zarate CA, Sarmiento E, López-Narvaez ML, Nicolini H, Genis-Mendoza AD. Psychiatric Comorbidity in Mexican Adolescents with a Diagnosis of Eating Disorders Its Relationship with the Body Mass Index. International Journal Of Environmental Research And Public Health 2021, 18: 3900. PMID: 33917708, PMCID: PMC8068102, DOI: 10.3390/ijerph18083900.Peer-Reviewed Original ResearchConceptsBody mass indexComorbid psychiatric disordersMass indexPsychiatric comorbidityPsychiatric disordersED diagnosisHigher body mass indexMini International Neuropsychiatric InterviewMexican adolescentsPresence of comorbiditiesInternational Neuropsychiatric InterviewMajor depressive disorderBinge-eating disorderChildren/adolescentsPrevalent comorbiditiesNeuropsychiatric InterviewDepressive disorderComorbiditiesGeneral populationDisorder prevalenceSevere metabolic disruptionsIntegrative treatmentMetabolic disruptionSuicide riskPrevalence