2013
Sustained delivery of proangiogenic microRNA‐132 by nanoparticle transfection improves endothelial cell transplantation
Devalliere J, Chang WG, Andrejecsk JW, Abrahimi P, Cheng CJ, Jane‐wit D, Saltzman WM, Pober JS. Sustained delivery of proangiogenic microRNA‐132 by nanoparticle transfection improves endothelial cell transplantation. The FASEB Journal 2013, 28: 908-922. PMID: 24221087, PMCID: PMC3898640, DOI: 10.1096/fj.13-238527.Peer-Reviewed Original ResearchConceptsHuman umbilical vein ECsEndothelial cellsMiR-132MicroRNA-132Cultured human umbilical vein endothelial cellsNumber of microvesselsGrowth factor-induced proliferationHuman umbilical vein endothelial cellsUmbilical vein endothelial cellsEndothelial cell transplantationCultured endothelial cellsEndogenous growth factorsEC transplantationVein endothelial cellsCell transplantationImmunodeficient miceTissue perfusionTransplantationMiR deliveryGrowth factorIntegrin αvβ3Endocytosed nanoparticlesSquare millimeterBiological effectsControl transfectionPericytes modulate endothelial sprouting
Chang WG, Andrejecsk JW, Kluger MS, Saltzman WM, Pober JS. Pericytes modulate endothelial sprouting. Cardiovascular Research 2013, 100: 492-500. PMID: 24042014, PMCID: PMC3826704, DOI: 10.1093/cvr/cvt215.Peer-Reviewed Original ResearchMeSH KeywordsBecaplerminCoculture TechniquesCulture Media, ConditionedHepatocyte Growth FactorHuman Umbilical Vein Endothelial CellsHumansMicrovesselsNeovascularization, PhysiologicParacrine CommunicationPericytesProto-Oncogene Proteins c-bcl-2Proto-Oncogene Proteins c-sisSignal TransductionSpheroids, CellularTime FactorsTransfectionVascular Endothelial Growth Factor A
2000
Control of Apoptosis during Angiogenesis by Survivin Expression in Endothelial Cells
O'Connor D, Schechner J, Adida C, Mesri M, Rothermel A, Li F, Nath A, Pober J, Altieri D. Control of Apoptosis during Angiogenesis by Survivin Expression in Endothelial Cells. American Journal Of Pathology 2000, 156: 393-398. PMID: 10666367, PMCID: PMC1850029, DOI: 10.1016/s0002-9440(10)64742-6.Peer-Reviewed Original ResearchMeSH KeywordsApoptosisCell DivisionCell SurvivalCells, CulturedEndothelial Growth FactorsEndothelium, VascularFibroblast Growth Factor 2HumansInhibitor of Apoptosis ProteinsLymphokinesMicrotubule-Associated ProteinsMitogensNeoplasm ProteinsNeovascularization, PhysiologicProteinsSurvivinVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsConceptsTumor necrosis factor alpha/cycloheximideControl of apoptosisEndothelial cellsSurvivin expressionQuiescent endothelial cellsEndothelial cell survivalGrowth factorApoptosis inhibitor survivinTwo-dimensional cultureCaspase-3 activityRecombinant expressionFibroblast growth factorBasic fibroblast growth factorCell survivalStrong inductionProtein survivinPathological angiogenesisProtective genesRNA expressionVascular tubesSurvivinExpressionVascular endothelial growth factorApoptosisCells
1998
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
Cines DB, Pollak ES, Buck CA, Loscalzo J, Zimmerman GA, McEver RP, Pober JS, Wick TM, Konkle BA, Schwartz BS, Barnathan ES, McCrae KR, Hug BA, Schmidt AM, Stern DM. Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 1998, 91: 3527-61. PMID: 9572988.Peer-Reviewed Original ResearchAnimalsArteriosclerosisBlood CellsBlood CoagulationCell AdhesionCell Adhesion MoleculesCell DifferentiationCells, CulturedEndothelial Growth FactorsEndothelinsEndothelium, VascularEpoprostenolExtracellular MatrixFemaleFibrinolysisFibroblast Growth Factor 2HemodynamicsHumansInflammationLymphokinesMaleMiceNeovascularization, PhysiologicNitric OxidePlatelet Activating FactorPre-EclampsiaPregnancyThrombosisUmbilical VeinsVascular DiseasesVascular Endothelial Growth Factor AVascular Endothelial Growth Factors