1989
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis.
Zavoico GB, Ewenstein BM, Schafer AI, Pober JS. IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis. The Journal Of Immunology 1989, 142: 3993-9. PMID: 2497185, DOI: 10.4049/jimmunol.142.11.3993.Peer-Reviewed Original ResearchMeSH KeywordsArachidonic AcidArachidonic AcidsCells, CulturedChromatography, Thin LayerCycloheximideDrug SynergismEndothelium, VascularEpoprostenolHistamineHumansInterleukin-1Platelet Activating FactorProstaglandin Endoperoxides, SyntheticProstaglandin H2Prostaglandins HThrombinVon Willebrand Factor
1987
Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells
Pober J. Effects of Tumour Necrosis Factor and Related Cytokines on Vascular Endothelial Cells. Novartis Foundation Symposia 1987, 131: 170-191. PMID: 3330009, DOI: 10.1002/9780470513521.ch12.Peer-Reviewed Original ResearchConceptsIL-1 betaHuman endothelial cellsIL-1 alphaRelated cytokinesVascular endothelial cellsEndothelial cellsNecrosis factorEndothelial leucocyte adhesion moleculeIntercellular adhesion molecule-1Tumor necrosis factorInterleukin-1 betaAdhesion molecule-1Endothelial cell activationInterleukin-1 alphaCultured human endothelial cellsPhorbol esterEffects of TNFRecombinant human TNFCytoplasmic calcium concentrationIL-1 speciesMechanism of actionHEC adhesivenessInflammatory leucocytesCell surface expressionProtein kinase C pathway