2022
The role of Vertebral Augmentation Procedures in the management of vertebral compression fractures secondary to multiple myeloma
Eseonu K, Panchmatia J, Streetly M, Grauer J, Fakouri B. The role of Vertebral Augmentation Procedures in the management of vertebral compression fractures secondary to multiple myeloma. Hematological Oncology 2022, 41: 323-334. PMID: 36440820, DOI: 10.1002/hon.3102.Peer-Reviewed Original ResearchMeSH KeywordsBone CementsFractures, CompressionHumansMultiple MyelomaOsteoporotic FracturesPainSpinal FracturesTreatment OutcomeConceptsVertebral augmentation proceduresVertebral compression fracturesMid-vertebral heightBalloon kyphoplastyMultiple myelomaPain controlCompression fracturesSpinal lesionsCurrent evidenceLong-term pain controlAugmentation proceduresNew oncological therapiesNon-operative managementEfficacy of vertebroplastySuperior functional outcomesFractured vertebral bodyVertebral body heightSoft tissue massSoft tissue lesionsSpinal bracingPalliative radiotherapySegmental kyphosisSurgical decompressionKyphotic deformitySerious complications
2018
Thromboembolic Events After Traumatic Vertebral Fractures
Samuel AM, Diaz-Collado PJ, Gala RJ, Webb ML, Lukasiewicz AM, Basques BA, Bohl DD, Kim HJ, Grauer JN. Thromboembolic Events After Traumatic Vertebral Fractures. Spine 2018, 43: 1289-1295. PMID: 29538240, DOI: 10.1097/brs.0000000000002634.Peer-Reviewed Original ResearchConceptsVenous thromboembolism eventsTraumatic vertebral fracturesVertebral fracturesSpinal cord injuryOdds ratioCord injuryRisk factorsNational Trauma Data Bank Research Data SetLonger inpatient lengthPulmonary embolism eventsDeep vein thrombosisHigh-energy injuriesVertebral fracture patientsLength of stayAdditional risk factorsMultivariate logistic regressionSuch adverse outcomesOverall rateThromboembolism eventsHospital courseThromboembolic eventsFracture patientsVein thrombosisLonger LOSTrauma patients
2016
Spinal Fracture in Patients With Ankylosing Spondylitis
Lukasiewicz AM, Bohl DD, Varthi AG, Basques BA, Webb ML, Samuel AM, Grauer JN. Spinal Fracture in Patients With Ankylosing Spondylitis. Spine 2016, 41: 191-196. PMID: 26579959, DOI: 10.1097/brs.0000000000001190.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleSpinal fracturesAdverse eventsCervical fracturesSpinal columnHospital adverse eventsMortality of fracturesSmall case seriesSpinal cord injuryAnkylosed spinePatient demographicsRetrospective cohortThoracic fracturesCase seriesHigh morbidityInjury characteristicsInpatient stayMinor traumaCord injuryPatient populationCase reportInpatient SampleBACKGROUND DATAHigh riskPatients
2015
Bilateral Vertebral Artery Injury in a Patient with Upper Cervical Spine Fractures Leading to Fatal Vertebrobasilar Infarction: A Case Report
Golinvaux NS, Basques BA, Bohl DD, Laurans MS, Grauer JN. Bilateral Vertebral Artery Injury in a Patient with Upper Cervical Spine Fractures Leading to Fatal Vertebrobasilar Infarction: A Case Report. Orthopaedic Surgery 2015, 7: 281-285. PMID: 26311105, PMCID: PMC6583726, DOI: 10.1111/os.12187.Peer-Reviewed Case Reports and Technical NotesMortality Rates Associated With Odontoid and Subaxial Cervical Spine Fractures.
Miller CP, Golinvaux NS, Brubacher JW, Bohl DD, Deng Y, Grauer JN. Mortality Rates Associated With Odontoid and Subaxial Cervical Spine Fractures. The American Journal Of Orthopedics 2015, 44: e173-9. PMID: 26047001.Peer-Reviewed Original ResearchConceptsCervical spine fracturesSpine fracturesSex-matched counterpartsMortality rateSubaxial fracturesGeneral populationSubaxial cervical spine fracturesAge-matched dataAge-matched menNational Death IndexMortality of menRetrospective reviewDeath IndexEmergency departmentCervical spineLevel IDeath recordsElderly personsOlder individualsSurvivalMonthsDevastating consequencesFracturesAgeMen
2014
Morbidity, Mortality, and Readmission After Vertebral Augmentation
Toy JO, Basques BA, Grauer JN. Morbidity, Mortality, and Readmission After Vertebral Augmentation. Spine 2014, 39: 1943-1949. PMID: 25188603, DOI: 10.1097/brs.0000000000000563.Peer-Reviewed Original ResearchConceptsSerious adverse eventsAnesthesiologists class 4General health outcomesAdverse eventsVertebral augmentationInpatient statusRisk factorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseHealth outcomesPoor short-term outcomeQuality Improvement Program databasePostoperative mortality rateRetrospective cohort studyImprovement Program databaseShort-term outcomesVertebral compression fracturesVertebral augmentation proceduresAmerican SocietyNongeneral anesthesiaCohort studyPatient characteristicsPostoperative dayPulmonary diseaseCommon fracturesC7 pars fracture subadjacent to C7 pedicle screw instrumentation at the caudal end of a posterior cervical instrumentation construct.
Halim A, Grauer J. C7 pars fracture subadjacent to C7 pedicle screw instrumentation at the caudal end of a posterior cervical instrumentation construct. The American Journal Of Orthopedics 2014, 43: e137-9. PMID: 25046189.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAccidental FallsAdultBone ScrewsCervical VertebraeHumansMalePeriprosthetic FracturesSpinal FracturesSpinal FusionSpinal InjuriesConceptsPars fracturesPedicle screw instrumentationScrew instrumentationInstrumentation constructsInitial clinical symptomsCervical spine injuryCommon surgical practiceExcessive bone resectionCaudal endPosterior cervical instrumentationLevel of T2Mechanical fallInstrumented fusionPosterior fusionClinical symptomsSpine injuriesLabel indicationsBone resectionPosterior instrumentationCervical instrumentationUS FoodDrug AdministrationSurgical practiceDistal extensionComplications
2011
The Incidence of Noncontiguous Spinal Fractures and Other Traumatic Injuries Associated With Cervical Spine Fractures
Miller CP, Brubacher JW, Biswas D, Lawrence BD, Whang PG, Grauer JN. The Incidence of Noncontiguous Spinal Fractures and Other Traumatic Injuries Associated With Cervical Spine Fractures. Spine 2011, 36: 1532-1540. PMID: 21242872, DOI: 10.1097/brs.0b013e3181f550a6.Peer-Reviewed Original ResearchConceptsCervical spine fracturesSpine fracturesCervical spineCT scanSingle level 1 trauma centerRetrospective medical record reviewLevel 1 trauma centerNoncontiguous spinal fracturesCervical spine traumaMedical record reviewC7 fractureExtraspinal injuriesAcute fracturesPrompt diagnosisSpine traumaRecord reviewTrauma centerSpinal fracturesSpine injuriesInjury patternsAdditional injuriesCervical segmentsSpinal traumaMedical recordsTraumatic injury
2009
The Timing and Influence of MRI on the Management of Patients With Cervical Facet Dislocations Remains Highly Variable
Grauer JN, Vaccaro AR, Lee JY, Nassr A, Dvorak MF, Harrop JS, Dailey AT, Shaffrey CI, Arnold PM, Brodke DS, Rampersaud R. The Timing and Influence of MRI on the Management of Patients With Cervical Facet Dislocations Remains Highly Variable. Clinical Spine Surgery A Spine Publication 2009, 22: 96-99. PMID: 19342930, DOI: 10.1097/bsd.0b013e31816a9ebd.Peer-Reviewed Original ResearchMeSH KeywordsCervical VertebraeClinical ProtocolsData CollectionDecision Support TechniquesJoint DislocationsJointsMagnetic Resonance ImagingNeurosurgeryObserver VariationOrthopedicsPractice Patterns, Physicians'Professional PracticeSpinal FracturesSpinal FusionSpinal InjuriesSurveys and QuestionnairesTime FactorsTomography, X-Ray ComputedTractionConceptsTraumatic cervical facet dislocationCervical facet dislocationMagnetic resonance imagingComplete spinal cord injuryInfluence of MRIManagement of patientsFacet dislocationSpinal cord injuryOpen reductionCord injuryOrthopaedic surgeonsUtilization of MRIEvidence-based algorithmDifferent clinical scenariosDevastating injuriesNeurologic examinationDisc herniationLigamentous disruptionPlain radiographsClosed treatmentTomography scanPatient managementTreatment decisionsOpen treatmentSpine surgeonsSurvey of spine surgeons on attitudes regarding osteoporosis and osteomalacia screening and treatment for fractures, fusion surgery, and pseudoarthrosis
Dipaola CP, Bible JE, Biswas D, Dipaola M, Grauer JN, Rechtine GR. Survey of spine surgeons on attitudes regarding osteoporosis and osteomalacia screening and treatment for fractures, fusion surgery, and pseudoarthrosis. The Spine Journal 2009, 9: 537-544. PMID: 19328744, DOI: 10.1016/j.spinee.2009.02.005.Peer-Reviewed Original ResearchConceptsDual-energy X-ray absorptiometrySpine fracturesSpine surgeonsMetabolic laboratoriesRisk factorsPractice patternsInstrumentation failureSpinal arthrodesisIndependent risk factorSignificant risk factorsLow-energy fracturesSpinal fusion operationsMetabolic bone disordersDegenerative spine conditionsX-ray absorptiometryPreoperative treatmentElderly patientsFracture careInstrumented fusionTreatment patternsOsteoporosis screeningFusion surgerySpine conditionsBone densitySpine specialists
2006
Osteogenic Protein-1 Induced Gene Expression: Evaluation in a Posterolateral Spinal Pseudarthrosis Model
White AP, Maak TG, Prince D, Vaccaro AR, Albert TJ, Hilibrand AS, Grauer JN. Osteogenic Protein-1 Induced Gene Expression: Evaluation in a Posterolateral Spinal Pseudarthrosis Model. Spine 2006, 31: 2550-2555. PMID: 17047543, DOI: 10.1097/01.brs.0000240713.24367.42.Peer-Reviewed Original ResearchConceptsGene expressionOsteogenic protein-1Protein 1Differential gene expressionGlyceraldehyde-3-phosphate dehydrogenaseGene expression dataBone morphogenetic protein-2Morphogenetic protein-2Platelet-derived growthExpression dataTranscriptase-polymerase chain reactionPolymerase chain reactionMolecular studiesProtein 2Messenger ribonucleic acidRibonucleic acidChain reactionAdhesion moleculesCytokine gene expressionExpressionGrowth factorVascular endothelial growth factorEnhanced levelsEndothelial growth factorReverse transcriptase-polymerase chain reactionSubaxial cervical spine trauma.
Kwon BK, Vaccaro AR, Grauer JN, Fisher CG, Dvorak MF. Subaxial cervical spine trauma. Journal Of The American Academy Of Orthopaedic Surgeons 2006, 14: 78-89. PMID: 16467183, DOI: 10.5435/00124635-200602000-00003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSubaxial cervical spine injuriesCervical spine injurySpinal cord injurySpine injuriesCord injuryAcute spinal cord injurySevere spinal cord injuryCertain injury patternsAdministration of methylprednisoloneSpinous process fractureSubaxial cervical injuriesAccurate clinical historyCareful physical examinationNeurologic statusDefinitive managementNonsurgical managementPatient factorsCervical injuryClosed reductionNeurologic impairmentProcess fracturesEmergent managementInjury patternsPhysical examinationRadiographic evaluation
2005
Proposal of a modified, treatment-oriented classification of odontoid fractures
Grauer JN, Shafi B, Hilibrand AS, Harrop JS, Kwon BK, Beiner JM, Albert TJ, Fehlings MG, Vaccaro AR. Proposal of a modified, treatment-oriented classification of odontoid fractures. The Spine Journal 2005, 5: 123-129. PMID: 15749611, DOI: 10.1016/j.spinee.2004.09.014.Peer-Reviewed Original Research
2004
Similarities and Differences in the Treatment of Spine Trauma Between Surgical Specialties and Location of Practice
Grauer JN, Vaccaro AR, Beiner JM, Kwon BK, Hilibrand AS, Harrop JS, Anderson G, Hurlbert J, Fehlings MG, Ludwig SC, Hedlund R, Arnold PM, Bono CM, Brodke DS, Dvorak MF, Fischer CG, Sledge JB, Shaffrey CI, Schwartz DG, Sears WR, Dickman C, Sharan A, Albert TJ, Rechtine GR. Similarities and Differences in the Treatment of Spine Trauma Between Surgical Specialties and Location of Practice. Spine 2004, 29: 685-696. PMID: 15014280, DOI: 10.1097/01.brs.0000115137.11276.0e.Peer-Reviewed Original ResearchConceptsSpinal traumaNeurosurgical spine surgeonsTiming of surgerySole graft materialExperienced spinal surgeonsLocation of practiceSpine traumaAnterior approachLumbar injuriesSuch injuriesBACKGROUND DATASpinal surgeonsSpine surgeonsClinical scenariosClinical decisionLevel of agreementGraft materialSurgeonsSurgical specialtiesTraumaCharacteristics of respondentsSurgeryInjurySPSS softwareOrthopedists