2023
Decline in Separate Incision Autograft for Spine Surgery Over the Past Decade: A Fading “gold standard”
Rudisill K, Ratnasamy P, Maloy G, Grauer J. Decline in Separate Incision Autograft for Spine Surgery Over the Past Decade: A Fading “gold standard”. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 938-944. PMID: 37332184, DOI: 10.5435/jaaos-d-22-01029.Peer-Reviewed Original ResearchMeSH KeywordsAgedAutograftsBone TransplantationHumansIliumMedicareSpinal FusionSurgical WoundTransplantation, AutologousTransplantation, HomologousTreatment OutcomeUnited StatesConceptsElixhauser Comorbidity IndexSurgeon specialtySpinal fusionComorbidity indexSmoking statusGold standardIliac crest autograftPatient ageIndependent predictorsPatient factorsNonsurgical factorsCrest autograftSpine surgeryBone graftingSpine fusionIliac crestBone graftAutograftYounger ageSurgeryInsurance factorsSpinal boneCommon procedureInsurance plansAge
2022
Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients
Gillinov SM, Fosam A, Burroughs PJ, Schneble CA, McLaughlin WM, Moran J, Jimenez AE, Grauer JN, Medvecky MJ. Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients. The American Journal Of Sports Medicine 2022, 50: 2893-2899. PMID: 35916771, DOI: 10.1177/03635465221111115.Peer-Reviewed Original ResearchMeSH KeywordsCartilage DiseasesCartilage, ArticularChild, PreschoolChondrocytesFemaleHumansIncidenceKnee JointReoperationRisk FactorsTransplantation, AutologousConceptsBony realignment proceduresAutologous chondrocyte implantationBody mass indexPrimary Autologous Chondrocyte ImplantationRevision surgeryRisk factorsRealignment proceduresPostoperative yearKnee arthroplastyFemale sexChondrocyte implantationECI scoresElixhauser comorbidity index scoreChondral defectsComorbidity Index scoreKaplan-Meier analysisLarge national cohortUnicompartmental knee arthroplastyTotal knee arthroplastyOsteochondral allograft transplantationLevel of evidenceOsteochondral autograft transferArticular cartilage proceduresFull-thickness chondral defectsChondral procedures
2007
rhBMP-2 (ACS and CRM Formulations) Overcomes Pseudarthrosis in a New Zealand White Rabbit Posterolateral Fusion Model
Lawrence JP, Waked W, Gillon TJ, White AP, Spock CR, Biswas D, Rosenberger P, Troiano N, Albert TJ, Grauer JN. rhBMP-2 (ACS and CRM Formulations) Overcomes Pseudarthrosis in a New Zealand White Rabbit Posterolateral Fusion Model. Spine 2007, 32: 1206-1213. PMID: 17495777, DOI: 10.1097/brs.0b013e318054721e.Peer-Reviewed Original ResearchAnimalsBone Morphogenetic Protein 2Bone Morphogenetic ProteinsBone SubstitutesBone TransplantationChemistry, PharmaceuticalDisease Models, AnimalDrug CarriersFemaleHumansIliumLumbar VertebraeNicotineOsseointegrationPseudarthrosisRabbitsRecombinant ProteinsSpinal FusionTime FactorsTomography, X-Ray ComputedTransforming Growth Factor betaTransplantation, Autologous
2006
Healos/Recombinant Human Growth and Differentiation Factor-5 Induces Posterolateral Lumbar Fusion in a New Zealand White Rabbit Model
Magit DP, Maak T, Trioano N, Raphael B, Hamouria Q, Polzhofer G, Drespe I, Albert TJ, Grauer JN. Healos/Recombinant Human Growth and Differentiation Factor-5 Induces Posterolateral Lumbar Fusion in a New Zealand White Rabbit Model. Spine 2006, 31: 2180-2188. PMID: 16946651, DOI: 10.1097/01.brs.0000232823.82106.0a.Peer-Reviewed Original ResearchConceptsRecombinant human growthDifferentiation factor 5Fusion ratePosterolateral lumbar spine fusionPosterolateral lumbar fusionIliac crest autograftLumbar spine fusionNew Zealand white rabbitsNew Zealand white rabbit modelZealand white rabbitsRabbit fusion modelWhite rabbit modelIntertransverse process fusionBone graft alternativesCrest autograftLumbar fusionBACKGROUND DATAHistologic differencesPreclinical studiesSpine fusionTreatment groupsFactor 5Histologic analysisBone graftFusion mass
2004
Development of a New Zealand White Rabbit Model of Spinal Pseudarthrosis Repair and Evaluation of the Potential Role of OP-1 to Overcome Pseudarthrosis
Grauer JN, Vaccaro AR, Kato M, Kwon BK, Beiner JM, Patel TC, Hilibrand AS, Chiba K, Albert TJ. Development of a New Zealand White Rabbit Model of Spinal Pseudarthrosis Repair and Evaluation of the Potential Role of OP-1 to Overcome Pseudarthrosis. Spine 2004, 29: 1405-1412. PMID: 15223930, DOI: 10.1097/01.brs.0000129028.25671.96.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBone Morphogenetic Protein 7Bone Morphogenetic ProteinsCotinineDrug Evaluation, PreclinicalFemaleHumansIliumInfusion Pumps, ImplantableLumbar VertebraeNicotinePostoperative ComplicationsPseudarthrosisRabbitsRadiographyRecombinant ProteinsSingle-Blind MethodSpinal DiseasesSpinal FusionTransforming Growth Factor betaTransplantation, AutologousWound HealingConceptsNew Zealand white rabbitsPosterolateral lumbar fusionOsteogenic protein-1Zealand white rabbitsLumbar fusionPseudarthrosis repairFusion massFusion rateWhite rabbitsManual palpationIliac crest autograftNew Zealand white rabbit modelTreatment of pseudarthrosesRabbit fusion modelWhite rabbit modelPresence of nicotineCrest autograftBACKGROUND DATAPseudarthrosesComputed tomographyAnimal modelsRabbit modelAutograftGraftWeeks