2023
Sponsorship of clinical trials related to the spine: Trends over time and comparative analysis of trial characteristics by sponsorship type
Caruana D, Jiang W, Elaydi A, Grauer J. Sponsorship of clinical trials related to the spine: Trends over time and comparative analysis of trial characteristics by sponsorship type. North American Spine Society Journal (NASSJ) 2023, 17: 100296. PMID: 38130466, PMCID: PMC10733670, DOI: 10.1016/j.xnsj.2023.100296.Peer-Reviewed Original ResearchTrial characteristicsClinical trialsIntervention typePhases of studyTrial registration dataInternet-based registryLack of randomizationCross-sectional analysisResults databaseDifferent intervention typesMultivariate analysisIncomplete reportingTrialsSponsorship typesSpineRandomizationRegistration dataIndustry sponsorshipStart yearRegistry
2022
Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials
Caruana DL, Kim D, Galivanche AR, David WB, Justen MA, Moushey AM, Sheth AH, Paranjpe MD, Grauer JN. Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials. Clinical Spine Surgery A Spine Publication 2022, 35: e596-e600. PMID: 35351841, DOI: 10.1097/bsd.0000000000001323.Peer-Reviewed Original ResearchConceptsClinical trialsTrial terminationTrial characteristicsMultivariate analysisCross-sectional analysisInvestigation of drugsInsufficient accrualResults databaseInterventional studyDetermine predictorsClinical studiesBACKGROUND DATACommon reasonAssess reasonsRecruitment statusTrialsPredictors of terminationSearch termsSpineCompletion ratesRegistryPredictorsStudyTermination
2011
Neurogenic and Myopathic Deformities of the Cervical Spine
Blizzard D, Hustedt J, Grauer J. Neurogenic and Myopathic Deformities of the Cervical Spine. Seminars In Spine Surgery 2011, 23: 206-209. DOI: 10.1053/j.semss.2011.04.001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSurgical interventionCervical spineCommon systemic conditionsSpectrum of etiologiesUnique management challengesReversible causesReversible symptomsNeurologic deficitsSymptomatic controlSymptomatic patientsSystemic treatmentKyphotic deformityClinical presentationProgressive conditionSystemic conditionsTreatment strategiesCommon causeEffective treatmentSpine surgeonsClinical scenariosDeformityPatientsEtiologySpineIntervention
2010
Normal Functional Range of Motion of the Lumbar Spine During 15 Activities of Daily Living
Bible JE, Biswas D, Miller CP, Whang PG, Grauer JN. Normal Functional Range of Motion of the Lumbar Spine During 15 Activities of Daily Living. Clinical Spine Surgery A Spine Publication 2010, 23: 106-112. PMID: 20065869, DOI: 10.1097/bsd.0b013e3181981823.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultBiomechanical PhenomenaElectrodiagnosisFemaleHumansIntervertebral DiscLumbar VertebraeMaleMiddle AgedMovementOutcome Assessment, Health CareProspective StudiesRange of Motion, ArticularReference ValuesTask Performance and AnalysisYoung AdultZygapophyseal JointConceptsFull active ROMLumbar spineAsymptomatic subjectsActive ROMFunctional ROMDaily livingFlexion/extensionProspective clinical studyLateral bending radiographsDynamic flexion/extensionNormal functional rangeIntraclass correlation coefficientLumbar ROMPreoperative impairmentPostsurgical outcomesClinical studiesBACKGROUND DATALumbar rangeLumbar motionSpinal ROMConsecutive daysADLRadiographic measurementsSpineROM values
2009
Radiation Exposure from Musculoskeletal Computerized Tomographic Scans
Biswas D, Bible JE, Bohan M, Simpson AK, Whang PG, Grauer JN. Radiation Exposure from Musculoskeletal Computerized Tomographic Scans. Journal Of Bone And Joint Surgery 2009, 91: 1882-1889. PMID: 19651945, DOI: 10.2106/jbjs.h.01199.Peer-Reviewed Original ResearchConceptsComputerized tomographic scanTomographic scanMean effective dosesEffective dosesEffective doseRadiation exposureEffective dose valuesElevated radiation exposureMusculoskeletal conditionsSingle institutionUpper extremityDosesNational Radiological Protection BoardHip scansDoseAppendicular skeletonScansAnatomic structuresPrior groupChestAbdomenPelvisExtremitiesSpineCurrent studyCurrent Trends in Spinal Arthroplasty
Whang PG, Simpson AK, Rechtine G, Grauer JN. Current Trends in Spinal Arthroplasty. Clinical Spine Surgery A Spine Publication 2009, 22: 26-33. PMID: 19190431, DOI: 10.1097/bsd.0b013e3181659804.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLumbar total disc arthroplastyTotal disc arthroplastyCervical total disc arthroplastySpine surgeonsNeurosurgical spine surgeonsAlternative surgical treatmentLong-term outcomesPercentage of surgeonsDegenerative spinal conditionsSpinal fusion proceduresOpinions of surgeonsSurgical treatmentDisc arthroplastyBACKGROUND DATASpinal conditionsDegenerative conditionsSurgeonsContemporary updateSpinal arthroplastyFusion proceduresArthroplastyDeleterious effectsSpineTreatmentSurvey studyThe Assessment of Cervical Foramina With Oblique Radiographs: The Effect of Film Angle on Foraminal Area
Simpson AK, Sabino J, Whang P, Emerson JW, Grauer JN. The Assessment of Cervical Foramina With Oblique Radiographs: The Effect of Film Angle on Foraminal Area. Clinical Spine Surgery A Spine Publication 2009, 22: 21-25. PMID: 19190430, DOI: 10.1097/bsd.0b013e3181639b62.Peer-Reviewed Original ResearchConceptsForaminal areaEntire cervical spineCervical spineForaminal dimensionsCervical foraminaCervical radiographsOblique radiographsCervical spine levelsHuman cadaveric cervical spinesCadaveric cervical spine specimensUpper cervical spineCadaveric cervical spinesGood interobserver reliabilityCervical spine specimensRadiographic evaluationC7-T1BACKGROUND DATASpine levelRadiographsInterobserver reliabilityRight sideSpineForamen sizeSpine specimensFreehand method
2007
The Utility of Dynamic Flexion-Extension Radiographs in the Initial Evaluation of the Degenerative Lumbar Spine
Hammouri QM, Haims AH, Simpson AK, Alqaqa A, Grauer JN. The Utility of Dynamic Flexion-Extension Radiographs in the Initial Evaluation of the Degenerative Lumbar Spine. Spine 2007, 32: 2361-2364. PMID: 17906579, DOI: 10.1097/brs.0b013e318155796e.Peer-Reviewed Original ResearchConceptsDynamic flexion-extension radiographsFlexion-extension radiographsDegenerative lumbar spineInitial evaluationRadiographic seriesLumbar spineLateral radiographsRetrospective radiographic reviewDynamic radiographsRadiographic reviewStanding anteroposteriorRadiograph seriesClinical managementLumbar complaintsBACKGROUND DATAInclusion criteriaInitial courseMost surgeonsDynamic filmsRadiographsLateral filmsAnteroposteriorPotential roleSpineLumbar images
2006
Necrotizing Infection of the Spine
Spock CR, Miki RA, Shah RV, Grauer JN. Necrotizing Infection of the Spine. Spine 2006, 31: e342-e344. PMID: 16688026, DOI: 10.1097/01.brs.0000217631.73632.37.Peer-Reviewed Original ResearchConceptsNecrotizing infectionAggressive surgical debridementMultifocal necrotizing fasciitisMultisystem organ failureSite of involvementDiabetic foot ulcersLumbar involvementSurgical debridementDiabetic patientsNecrotizing fasciitisOrgan failureFoot ulcersFatal conditionCase reportSuch infectionsBACKGROUND DATALumbar spineInfectionPatientsSpinal componentsSoft tissueSpineFasciitisPotential focusGrave consequences
2004
Predictors of paralysis in the rheumatoid cervical spine in patients undergoing total joint arthroplasty.
Grauer JN, Tingstad EM, Rand N, Christie MJ, Hilibrand AS. Predictors of paralysis in the rheumatoid cervical spine in patients undergoing total joint arthroplasty. Journal Of Bone And Joint Surgery 2004, 86: 1420-4. PMID: 15252088, DOI: 10.2106/00004623-200407000-00009.Peer-Reviewed Original ResearchConceptsTotal joint arthroplastyPredictors of paralysisRadiographic evidenceRheumatoid arthritisCervical spineJoint arthroplastyCervical instabilityPosterior atlantodental intervalRheumatoid cervical spinePopulation of patientsExtension lateral radiographsOrthopaedic manifestationsAtlantodental intervalRadiographic findingsRadiographic predictorsSpinal cordRadiographic signsLateral radiographsPatientsArthritisParalysisArthroplastyRadiographsFive-year periodSpine
1998
Biomechanics of whiplash injury
Panjabi MM, Cholewicki J, Nibu K, Grauer JN, Babat LB, Dvorak J, Bär HF. Biomechanics of whiplash injury. Die Orthopädie 1998, 27: 813-819. PMID: 9894235, DOI: 10.1007/pl00003468.Peer-Reviewed Original ResearchConceptsCervical spineHuman cadaveric specimensVertebral arteryWhiplash injuryWhiplash traumaInjury mechanismCadaveric specimensHyper-extension injuryC6-C7 levelEffective injury preventionLower cervical spineUnderlying injury mechanismClinical symptomsTrauma CTVertebral alignmentInjury preventionMRI scansInjuryWhiplashCapsular ligamentsFunctional radiographsSpineTraumaVulnerable phaseArteryMechanism of whiplash injury
Panjabi MM, Cholewicki J, Nibu K, Grauer JN, Babat LB, Dvorak J. Mechanism of whiplash injury. Clinical Biomechanics 1998, 13: 239-249. PMID: 11415793, DOI: 10.1016/s0268-0033(98)00033-3.Peer-Reviewed Original ResearchCervical spineWhiplash traumaInjury mechanismVertebral arteryWhiplash injuryFunctional radiographyCapsular ligamentsC6-C7 levelCadaveric cervical spine specimensHuman cadaveric cervical spine specimensSpine specimensLower cervical spineWhiplash injury mechanismHuman cadaveric spine specimensCervical spine specimensAnterior injuryAnatomic alignmentCadaveric spine specimensCT scanInjuryTraumaLow levelsWhiplashBiomechanical studySpine