2024
Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report
Hough R, Alvira C, Bastarache J, Erzurum S, Kuebler W, Schmidt E, Shimoda L, Abman S, Alvarez D, Belvitch P, Bhattacharya J, Birukov K, Chan S, Cornfield D, Dudek S, Garcia J, Harrington E, Hsia C, Islam M, Jonigk D, Kalinichenko V, Kolb T, Lee J, Mammoto A, Mehta D, Rounds S, Schupp J, Shaver C, Suresh K, Tambe D, Ventetuolo C, Yoder M, Stevens T, Damarla M. Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report. American Journal Of Respiratory Cell And Molecular Biology 2024, 71: 388-406. PMID: 39189891, PMCID: PMC11450313, DOI: 10.1165/rcmb.2024-0330st.Peer-Reviewed Original ResearchVascular diseaseEndothelial cell injuryAmerican Thoracic SocietyEndothelial cell functionPulmonary endotheliumMechanical propertiesLung endotheliumChronic vascular diseaseEndothelial functionPathophysiological mechanismsHealth and DiseaseVascular locationThoracic SocietyCell injuryEndotheliumCell functionTissue compartmentsDiseaseVascular circuitBidirectional signalingTranslation of discoveriesBlood
2021
A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds
Yuan Y, Leiby KL, Greaney AM, Raredon MSB, Qian H, Schupp JC, Engler AJ, Baevova P, Adams TS, Kural MH, Wang J, Obata T, Yoder MC, Kaminski N, Niklason LE. A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds. Frontiers In Bioengineering And Biotechnology 2021, 9: 760309. PMID: 34869270, PMCID: PMC8640093, DOI: 10.3389/fbioe.2021.760309.Peer-Reviewed Original ResearchVascular diseaseEndothelial phenotypeLung vascular diseaseAcute lung injuryPulmonary microvascular functionWhole lung scaffoldsVascular barrier functionLung injuryMicrovascular functionEndothelial cell coverageSingle-cell RNA-sequencing analysisLPS treatmentProinflammatory signalsWhole lungLung endotheliumLung systemVascular barrierOrgan engineering approachesBarrier functionLungWhole-organ scaffoldsVascular structuresDrug mechanismsEndotheliumDisease