Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex
DeFelipe J, Arellano J, Merchán-Pérez A, González-Albo M, Walton K, Llinás R. Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex. Cerebral Cortex 2002, 12: 883-891. PMID: 12122037, DOI: 10.1093/cercor/12.8.883.Peer-Reviewed Original ResearchConceptsLayers II/IIISynaptic circuitrySynaptic densityFlight animalsLaminar-specific mannerLower synaptic densityDensity of synapsesDays of spaceflightAsymmetrical synapsesCortical synapsesLayer IVCortical synaptogenesisLong-term spaceflightControl animalsDeveloping NeocortexAdult patternCortical organizationNeocortical circuitrySynapsesGround control animalsMonth periodSignificant differencesFuture long-term spaceflightsAnimalsNeocortical representationsMicrostructure of the neocortex: Comparative aspects
DeFelipe J, Alonso-Nanclares L, Arellano J. Microstructure of the neocortex: Comparative aspects. Brain Cell Biology 2002, 31: 299-316. PMID: 12815249, DOI: 10.1023/a:1024130211265.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological EvolutionCell CountHumansMicroscopy, ElectronNeocortexNeuropilSpecies SpecificitySynapsesConceptsDifferent cortical areasCortical areasExtrinsic afferent systemsNeocortex of humansInhibitory GABAergic interneuronsDensity of excitatoryNumber of synapsesSpecific cortical circuitsDistinct cortical areasSpiny cellsInhibitory circuitsGABAergic interneuronsInhibitory synapsesNeocortical neuronsNeuronal elementsPyramidal cellsAfferent systemsCortical circuitsNeocortical circuitsCortical tissueNumber of neuronsNeocortexNeuronsExcitatoryBasic microcircuit