Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex
DeFelipe J, Arellano J, Merchán-Pérez A, González-Albo M, Walton K, Llinás R. Spaceflight Induces Changes in the Synaptic Circuitry of the Postnatal Developing Neocortex. Cerebral Cortex 2002, 12: 883-891. PMID: 12122037, DOI: 10.1093/cercor/12.8.883.Peer-Reviewed Original ResearchConceptsLayers II/IIISynaptic circuitrySynaptic densityFlight animalsLaminar-specific mannerLower synaptic densityDensity of synapsesDays of spaceflightAsymmetrical synapsesCortical synapsesLayer IVCortical synaptogenesisLong-term spaceflightControl animalsDeveloping NeocortexAdult patternCortical organizationNeocortical circuitrySynapsesGround control animalsMonth periodSignificant differencesFuture long-term spaceflightsAnimalsNeocortical representationsPSA-NCAM Immunoreactivity in Chandelier Cell Axon Terminals of the Human Temporal Cortex
Arellano J, DeFelipe J, Muñoz A. PSA-NCAM Immunoreactivity in Chandelier Cell Axon Terminals of the Human Temporal Cortex. Cerebral Cortex 2002, 12: 617-624. PMID: 12003861, DOI: 10.1093/cercor/12.6.617.Peer-Reviewed Original ResearchConceptsChandelier cell axon terminalsPSA-NCAMLayers IIAxon terminalsPlastic changesAdult central nervous systemPSA-NCAM immunoreactivityDouble immunocytochemical stainingHuman temporal cortexHuman entorhinal cortexCentral nervous systemPV-immunoreactiveTemporal neocortexSerotonin receptorsEntorhinal cortexTemporal cortexNervous systemAxonal processesGABA transporterImmunocytochemical stainingGAT-1ParvalbuminNeocortexCortexPresent study