2011
Parathyroid Hormone-Related Protein Is Not Required for Normal Ductal or Alveolar Development in the Post-Natal Mammary Gland
Boras-Granic K, VanHouten J, Hiremath M, Wysolmerski J. Parathyroid Hormone-Related Protein Is Not Required for Normal Ductal or Alveolar Development in the Post-Natal Mammary Gland. PLOS ONE 2011, 6: e27278. PMID: 22087279, PMCID: PMC3210770, DOI: 10.1371/journal.pone.0027278.Peer-Reviewed Original ResearchConceptsMammary glandPTHrP expressionAlveolar developmentMyoepithelial cellsMaternal calcium homeostasisOverexpression of PTHrPRole of PTHrPExpression of PTHrPEmbryonic mammary budPTHrP deficiencyMouse mammary glandParathyroid hormoneTransgenic miceDuctal developmentCalcium homeostasisAlveolar cellsPTHrPPubertal developmentMMTV-CrePost-natal mammary glandMammary developmentMammary budPostnatal mammary glandCre transgenePTHrP gene
1995
Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development
Wysolmerski J, McCaughern-Carucci J, Daifotis A, Broadus A, Philbrick W. Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development. Development 1995, 121: 3539-3547. PMID: 8582268, DOI: 10.1242/dev.121.11.3539.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell Culture TechniquesDrug ImplantsEpitheliumFemaleGene ExpressionImmunohistochemistryMammary Glands, AnimalMesodermMiceMice, TransgenicMolecular Sequence DataMorphogenesisParathyroid HormoneParathyroid Hormone-Related ProteinPolymerase Chain ReactionProteinsReceptors, Parathyroid HormoneSignal TransductionConceptsHormone-related proteinBreast developmentTransgenic miceParathyroid hormoneMyoepithelial cellsPTH/PTHrP receptorParathyroid hormone-related proteinMammary glandMammary duct systemOverexpression of PTHrPNormal breast developmentSlow-release pelletsEffects of PTHrPNormal fetal tissuesMammary gland developmentHumoral hypercalcemiaBreast hypoplasiaTumor productsPTHrP receptorNormal miceLobuloalveolar developmentTerminal ductsPTHrPFetal tissuesMice impairs