2011
Site‐specific changes in bone microarchitecture, mineralization, and stiffness during lactation and after weaning in mice
Liu XS, Ardeshirpour L, VanHouten JN, Shane E, Wysolmerski JJ. Site‐specific changes in bone microarchitecture, mineralization, and stiffness during lactation and after weaning in mice. Journal Of Bone And Mineral Research 2011, 27: 865-875. PMID: 22189918, DOI: 10.1002/jbmr.1503.Peer-Reviewed Original ResearchConceptsWhole bone stiffnessNulliparous miceBone microarchitectureTissue mineralizationBone mineral density BMDIndividual trabecula segmentationDramatic bone lossBone mineral densityBone stiffnessRecovered miceBone lossMineral densityPup weaningEffect of lactationMouse modelSkeletal sitesBone quantityClinical observationsMicro-finite element analysisBone qualitySite-specific changesSkeletal changesDigital topological analysisMiceCortical structures
2010
Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis
Coletta RD, McCoy EL, Burns V, Kawakami K, McManaman JL, Wysolmerski JJ, Ford HL. Characterization of the Six1 homeobox gene in normal mammary gland morphogenesis. BMC Developmental Biology 2010, 10: 4. PMID: 20074369, PMCID: PMC2823684, DOI: 10.1186/1471-213x-10-4.Peer-Reviewed Original ResearchConceptsNormal mammary gland developmentAdult mammary glandMammary gland developmentMammary glandMammary developmentBreast cancerMouse modelBreast tumorigenesisEmbryonic mammary glandPostnatal mammary developmentRag1-/- miceNormal mammary gland morphogenesisGland developmentTransgenic mouse modelBreast cancer initiationViable therapeutic targetIndependent mouse modelsAdult mouse mammary glandAnti-cancer therapyMammary stem cellsFamily membersMouse mammary glandUnwanted side effectsRole of Six1Invasive carcinoma
2001
Mammary ductal and alveolar development: Lesson learned from genetically manipulated mice
Dunbar M, Wysolmerski J. Mammary ductal and alveolar development: Lesson learned from genetically manipulated mice. Microscopy Research And Technique 2001, 52: 163-170. PMID: 11169864, DOI: 10.1002/1097-0029(20010115)52:2<163::aid-jemt1002>3.0.co;2-r.Peer-Reviewed Original ResearchConceptsMammary developmentMammary gland developmentDevelopmental biologistsMouse genomeMammary glandCertain genesKnockout technologyMolecular mechanismsGland developmentDuctal developmentFundamental processesAlveolar developmentGenomeRecent advancesMouse modelGenesMechanismBiologistsTransgenicDifferentiationIntensive effortsMoleculesExpressionGlandDevelopment