2020
Association of Treatment Inequity and Ancestry With Pancreatic Ductal Adenocarcinoma Survival
Heller DR, Nicolson NG, Ahuja N, Khan S, Kunstman JW. Association of Treatment Inequity and Ancestry With Pancreatic Ductal Adenocarcinoma Survival. JAMA Surgery 2020, 155: e195047. PMID: 31800002, PMCID: PMC6902102, DOI: 10.1001/jamasurg.2019.5047.Peer-Reviewed Original ResearchConceptsPancreatic ductal adenocarcinomaNational Cancer DatabaseWhite patientsBlack patientsAdvanced diseaseOverall survivalClinical parametersDisease stageCancer DatabaseSurgical proceduresMultivariable Cox proportional hazards regression modelingTreatment inequitiesCox proportional hazards regression modelingPancreatic ductal adenocarcinoma (PDAC) survivalUnadjusted median overall survivalYounger ageProportional hazards regression modelingMedian overall survivalModest survival advantageStage II diseaseNew cancer diagnosesLess chemotherapyResectable cancerCohort studyPrimary outcome
2015
Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing
Kunstman JW, Juhlin CC, Goh G, Brown TC, Stenman A, Healy JM, Rubinstein JC, Choi M, Kiss N, Nelson-Williams C, Mane S, Rimm DL, Prasad ML, Höög A, Zedenius J, Larsson C, Korah R, Lifton RP, Carling T. Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing. Human Molecular Genetics 2015, 24: 2318-2329. PMID: 25576899, PMCID: PMC4380073, DOI: 10.1093/hmg/ddu749.Peer-Reviewed Original Research
2013
Nasogastric Drainage May Be Unnecessary after Pancreaticoduodenectomy: A Comparison of Routine vs Selective Decompression
Kunstman JW, Klemen ND, Fonseca AL, Araya DL, Salem RR. Nasogastric Drainage May Be Unnecessary after Pancreaticoduodenectomy: A Comparison of Routine vs Selective Decompression. Journal Of The American College Of Surgeons 2013, 217: 481-488. PMID: 23891073, DOI: 10.1016/j.jamcollsurg.2013.04.031.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overComorbidityConnecticutDecompression, SurgicalDrainageFemaleGastroparesisHumansIntubation, GastrointestinalMaleMiddle AgedMultivariate AnalysisPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsRetrospective StudiesTreatment OutcomeUnnecessary ProceduresConceptsLength of stayNasogastric decompressionNGT insertionPostoperative nasogastric tube useRoutine postoperative nasogastric decompressionNasogastric tube useOverall surgical morbidityPostoperative nasogastric decompressionOverall complication rateStandard of careAppropriate treatment strategyFirst patient cohortDietary toleranceSelective groupComparison of RoutineTreat mannerComplication rateNasogastric drainagePatient agePostoperative courseCommon indicationPrimary outcomeRoutine groupSingle surgeonSurgical morbidity
2012
Comprehensive Analysis of Variables Affecting Delayed Gastric Emptying Following Pancreaticoduodenectomy
Kunstman JW, Fonseca AL, Ciarleglio MM, Cong X, Hochberg A, Salem RR. Comprehensive Analysis of Variables Affecting Delayed Gastric Emptying Following Pancreaticoduodenectomy. Journal Of Gastrointestinal Surgery 2012, 16: 1354-1361. PMID: 22450953, DOI: 10.1007/s11605-012-1873-y.Peer-Reviewed Original ResearchConceptsIndependent risk factorDGE incidenceConsensus guidelinesRisk factorsComplicated post-operative courseDGE developmentAcademic tertiary centerPeri-operative variablesPost-operative abscessIntraoperative blood lossPost-operative eventsPost-operative courseSingle-surgeon databasePancreatic fistula formationInternational Consensus GroupPulmonary comorbiditiesBlood lossPylorus preservationTertiary centerFistula formationSecondary complicationsOperative bedOperative techniquePancreaticoduodenectomyConsensus group