Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates
Elsworth J, Redmond D, Roth R. Plasma and cerebrospinal fluid 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) as indices of brain norepinephrine metabolism in primates. Brain Research 1982, 235: 115-124. PMID: 7188317, DOI: 10.1016/0006-8993(82)90200-1.Peer-Reviewed Original ResearchConceptsConcentration of MHPGBrain areasNorepinephrine metabolismMHPG concentrationsCisternal CSFBrain norepinephrine metabolismFree MHPG concentrationsCentral noradrenergic activityNoradrenergic activityOccipital cortexFree MHPGMHPGBrain regionsCSFSignificant correlationUseful indexVervet monkeysMetabolismPlasmaCortex