2024
The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy
Liu M, Dong H, Mazlout A, Wu Y, Kalyanasundaram A, Oshinski J, Sun W, Elefteriades J, Leshnower B, Gleason R. The role of anatomic shape features in the prognosis of uncomplicated type B aortic dissection initially treated with optimal medical therapy. Computers In Biology And Medicine 2024, 170: 108041. PMID: 38330820, PMCID: PMC10932856, DOI: 10.1016/j.compbiomed.2024.108041.Peer-Reviewed Original ResearchConceptsType B aortic dissectionTreated with optimal medical therapyAortic growth rateOptimal medical therapyUncomplicated type B aortic dissectionB aortic dissectionMedical therapyCT scanPatients' long-term survivalType B aortic dissection patientsLong-term outcomesLong-term survivalFailure groupAortic expansionChronic phaseFailure patientsPatientsCT imagesTherapyDissectionStatistical shape modelFailurePrognosisScanningRegression
2023
Bicuspid aortopathy does not require earlier surgical intervention
Zafar M, Wu J, Vinholo T, Li Y, Papanikolaou D, Ellauzi H, Ostberg N, Kalyanasundaram A, Kalogerakos P, Mukherjee S, Ziganshin B, Rizzo J, Elefteriades J. Bicuspid aortopathy does not require earlier surgical intervention. Journal Of Thoracic And Cardiovascular Surgery 2023, 168: 760-769.e4. PMID: 37088130, DOI: 10.1016/j.jtcvs.2023.04.017.Peer-Reviewed Original ResearchBicuspid aortic valveAdverse aortic eventsEvent-free survivalAortic eventsAortic sizeAortic diameterAortic growth rateEarly surgical interventionLong-term complicationsRisk of complicationsThoracic aortic aneurysmAortic deathComplication rateSurgical repairOperative repairProphylactic surgerySurgical interventionAortic aneurysmAortic valveSurgical correctionBicuspid aortopathyRelative riskExpert centersTAV-ATAAPatientsFate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University
Wu J, Zafar M, Liu Y, Chen J, Li Y, Ziganshin B, Ellauzi H, Mukherjee S, Rizzo J, Elefteriades J. Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University. European Heart Journal 2023, 44: 4579-4588. PMID: 36994934, DOI: 10.1093/eurheartj/ehad148.Peer-Reviewed Original ResearchConceptsAdverse aortic eventsThoracic aortic aneurysmAortic sizeAortic aneurysmCox regressionAortic growthRisk factorsSignificant independent risk factorsMultivariable Cox regressionIndependent risk factorCohort of patientsUnivariable Cox regressionSignificant protective factorAortic deathATAA patientsAortic eventsPrimary endpointSurgical interventionThree-decade experienceNatural historyYearly riskProtective factorsAneurysmsPatientsIntervention criteriaFull calcium jacket: Conservative management of a traumatic aortic injury
Tripathi R, Ellauzi H, Zafar M, Ziganshin B, Elefteriades J. Full calcium jacket: Conservative management of a traumatic aortic injury. Journal Of Vascular Surgery Cases And Innovative Techniques 2023, 9: 101132. PMID: 37139352, PMCID: PMC10149390, DOI: 10.1016/j.jvscit.2023.101132.Peer-Reviewed Original ResearchKIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection
Velasco J, Li Y, Ziganshin B, Zafar M, Rizzo J, Ma D, Zang H, Kalyanasundaram A, Elefteriades J. KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. Genes 2023, 14: 252. PMID: 36833179, PMCID: PMC9956195, DOI: 10.3390/genes14020252.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic dissectionOdds ratioVariant statusArg allele carriersThoracic aortic dissectionOccurrence of ADAortic sizeArg alleleMarked adverse impactTAA patientsAortic aneurysmClinical assessmentSurgical decisionAllele carriersIncrease riskVariant patientsArg carriersPilot studyDissectionImportant intracellular functionsConfirmatory findingsPatientsAneurysmsPresent study
2022
Cerebrospinal Fluid Drainage for Prevention of Spinal Cord Ischemia in Thoracic Endovascular Aortic Surgery—Pros and Cons
Ellauzi H, Arora H, Elefteriades J, Zaffar M, Ellauzi R, Popescu W. Cerebrospinal Fluid Drainage for Prevention of Spinal Cord Ischemia in Thoracic Endovascular Aortic Surgery—Pros and Cons. Aorta 2022, 10: 290-297. PMID: 36539146, PMCID: PMC9767776, DOI: 10.1055/s-0042-1757792.Peer-Reviewed Original Research
2021
Ascending Aneurysms in Heart Transplant Patients A Rare Opportunity to Assess Heredity Versus Biological Environment
Anis O, Kopf G, Ziganshin B, Zafar M, Tranquilli M, Sieller R, Elefteriades J. Ascending Aneurysms in Heart Transplant Patients A Rare Opportunity to Assess Heredity Versus Biological Environment. JACC Case Reports 2021, 3: 1685-1689. PMID: 34766019, PMCID: PMC8571777, DOI: 10.1016/j.jaccas.2021.07.010.Peer-Reviewed Original ResearchDelayed Surgery for Acute Aortic Dissection
Pinkhasova P, Zafar M, Ziganshin B, Elefteriades J. Delayed Surgery for Acute Aortic Dissection. 2021, 535-551. DOI: 10.1007/978-3-030-66668-2_37.Peer-Reviewed Original ResearchA probabilistic and anisotropic failure metric for ascending thoracic aortic aneurysm risk assessment
Liu M, Liang L, Zou Q, Ismail Y, Lou X, Iannucci G, Chen E, Leshnower B, Elefteriades J, Sun W. A probabilistic and anisotropic failure metric for ascending thoracic aortic aneurysm risk assessment. Journal Of The Mechanics And Physics Of Solids 2021, 155: 104539. DOI: 10.1016/j.jmps.2021.104539.Peer-Reviewed Original ResearchATAA patientsAortic wallAortic tissue samplesThoracic aortic aneurysmAortic aneurysmAneurysm rupturePatientsRisk assessmentTissue samplesCharacteristic curveFailure metricsTsai-Hill failure criterionCT imagesRiskTensile failure testsMaximum principal stressRupture risk assessmentPrevious studiesAssessmentSimple Hepatic Cysts as Markers of Thoracic Aortic Disease
C K, BA Z, MA Z, J B, J E. Simple Hepatic Cysts as Markers of Thoracic Aortic Disease. Journal Of Disease Markers 2021, 6 DOI: 10.26420/jdismarkers.2021.1043.Peer-Reviewed Original ResearchThoracic aortic diseaseSimple hepatic cystsBovine aortic archBicuspid aortic valveSimple renal cystsPositive family historyMost patientsAortic diseaseHepatic cystsRetrospective studyAortic aneurysmAortic archAortic valveClinical markersHospital patientsFamily historyRenal cystsTAD patientsControl groupPatientsAneurysmsPrevalenceCystsDiseaseLeft Atrial Cannulation in Atrial Fibrillation
Elefteriades J, Ziganshin B. Left Atrial Cannulation in Atrial Fibrillation. 2021, 91-92. DOI: 10.1007/978-3-030-78877-3_32.Peer-Reviewed Original ResearchSiena Graft for Mega-Aorta
Elefteriades J, Ziganshin B. Siena Graft for Mega-Aorta. 2021, 99-102. DOI: 10.1007/978-3-030-78877-3_36.Peer-Reviewed Original ResearchV-Shaped Aortic Root Remodeling
Elefteriades J, Ziganshin B. V-Shaped Aortic Root Remodeling. 2021, 159-160. DOI: 10.1007/978-3-030-78877-3_53.Peer-Reviewed Original ResearchStand-Alone Elephant Trunk Procedure
Elefteriades J, Ziganshin B. Stand-Alone Elephant Trunk Procedure. 2021, 185-186. DOI: 10.1007/978-3-030-78877-3_59.Peer-Reviewed Original ResearchPulmonary Artery Aneurysms
Elefteriades J, Ziganshin B. Pulmonary Artery Aneurysms. 2021, 285-287. DOI: 10.1007/978-3-030-78877-3_69.Peer-Reviewed Original ResearchValve-Sparing Aortic Root Replacement
Elefteriades J, Ziganshin B. Valve-Sparing Aortic Root Replacement. 2021, 161-169. DOI: 10.1007/978-3-030-78877-3_54.Peer-Reviewed Original Research
2018
Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms
Findlay R, Thompson O, Ziganshin B, Elefteriades J. Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms. 2018, 107-118. DOI: 10.1016/b978-0-12-809979-7.00010-9.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmAortic diseaseGiant cell arteritisAortic arch abnormalitiesBicuspid aortic valveThoracic aortic diseaseAbdominal aortic aneurysmConnective tissue disordersCell arteritisClinical findingsHigh morbidityAortic valveIncidental findingArch abnormalitiesClinical markersFamily historyTissue disordersRenal cystsTAA developmentAneurysmsIntracranial aneurysmsEarly detectionDiseasePatients
2017
Two-Stage Elephant Trunk approach for open management of distal aortic arch and descending aortic pathology in patients with Marfan syndrome
Velasquez C, Zafar M, Saeyeldin A, Mahmood S, Brownstein A, Erben Y, Ziganshin B, Elefteriades J. Two-Stage Elephant Trunk approach for open management of distal aortic arch and descending aortic pathology in patients with Marfan syndrome. ASVIDE 2017, 4: 541-541. DOI: 10.21037/asvide.2017.541.Peer-Reviewed Original ResearchMechanisms of Disease and Natural History
Ziganshin B, Elefteriades J. Mechanisms of Disease and Natural History. 2017, 19-43. DOI: 10.1007/978-3-319-15192-2_2.Peer-Reviewed Original ResearchAortic diseaseNatural historyEndovascular treatment optionsThoracic aortic diseaseClassic open surgeryDiseased aortic wallEvidence-based criteriaMechanisms of diseaseAortic pathologyAortic ruptureLethal complicationOpen surgeryProphylactic treatmentEndovascular interventionTreatment optionsIndividual patientsAortic wallPersonalized managementMechanisms of developmentDiseasePatientsSuch treatmentTreatmentCurrent understandingComplications
2015
CHRONOLOGIC AND CLIMATIC FACTORS PRECIPITATE ACUTE AORTIC DISSECTION: A STUDY OF 1642 PATIENTS IN TWO CONTINENTS
Ma W, Li B, Ziganshin B, Zhang W, Wang L, Sarkar A, Pan X, Liu N, Zheng J, Liu Y, Zhu J, Huang L, Sun L, Elefteriades J. CHRONOLOGIC AND CLIMATIC FACTORS PRECIPITATE ACUTE AORTIC DISSECTION: A STUDY OF 1642 PATIENTS IN TWO CONTINENTS. Journal Of The American College Of Cardiology 2015, 65: a2112. DOI: 10.1016/s0735-1097(15)62112-x.Peer-Reviewed Original Research