2013
Late Anatomic Findings after “Rescue CABG” for Peri-Operative Ischemia Following Aortic Root Replacement
Ramarathnam A, Javier A, Farkas E, Cornfeld D, Tranquilli M, Elefteriades J. Late Anatomic Findings after “Rescue CABG” for Peri-Operative Ischemia Following Aortic Root Replacement. World Journal Of Cardiovascular Surgery 2013, 2013: 70-76. DOI: 10.4236/wjcs.2013.32012.Peer-Reviewed Original ResearchAortic root replacementRoot replacementCT angiogramIntra-aortic balloon pump placementVentricular assist device insertionGood late survivalYale-New HavenCoronary artery bypassTime of surgeryCoronary bypass graftsLong-term survivorsAcute myocardial ischemiaHospital mortalityArtery bypassPrompt recognitionBypass graftPatient chartsAnatomic causeOperative recordsTomographic angiogramUnstable hemodynamicsMyocardial ischemiaLate survivalDevice insertionVentricular fibrillation
2005
Mechanical deterioration underlies malignant behavior of aneurysmal human ascending aorta
Koullias G, Modak R, Tranquilli M, Korkolis DP, Barash P, Elefteriades JA. Mechanical deterioration underlies malignant behavior of aneurysmal human ascending aorta. Journal Of Thoracic And Cardiovascular Surgery 2005, 130: 677.e1-677.e9. PMID: 16153912, DOI: 10.1016/j.jtcvs.2005.02.052.Peer-Reviewed Original ResearchConceptsMechanical characteristicsMechanical deteriorationHuman ascending aortaAortic aneurysmAortic wall stressNormal aortaAneurysmal aortaAortic distensibilityAscending aortaMalignant behaviorAortic wallWall stressMaximal tensile strengthMechanical propertiesCoronary artery bypassTensile strengthTime of surgeryAortic wall thicknessAscending Aortic AneurysmMalignant clinical behaviorElastic modulusHuman ascending aortic aneurysmsEngineering analysisAneurysmal aortic wallMechanical substrate
2001
Myocardial Revascularization as a Therapeutic Strategy in the Patient with Advanced Ventricular Dysfunction
Mitropoulos F, Elefteriades J. Myocardial Revascularization as a Therapeutic Strategy in the Patient with Advanced Ventricular Dysfunction. Heart Failure Reviews 2001, 6: 163-175. PMID: 11391034, DOI: 10.1023/a:1011416929501.Peer-Reviewed Original ResearchConceptsCoronary artery bypassVentricular dysfunctionArtery bypassPerioperative managementEjection fractionPatient selectionAdvanced ventricular dysfunctionRight ventricular dysfunctionLeft ventricular dysfunctionLow ejection fractionOptimal perioperative managementSevere ventricular dysfunctionCareful patient selectionCoronary artery diseaseLong-term outcomesNumber of patientsQuality of lifeSurgical revascularizationHeart transplantationPulmonary hypertensionMyocardial revascularizationOverall prognosisArtery diseaseMedical managementRedo bypassSingle-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆
Kim R, Mariconda D, Tellides G, Kopf G, Dewar M, Lin Z, Elefteriades J. Single-clamp technique does not protect against cerebrovascular accident in coronary artery bypass grafting⋆. European Journal Of Cardio-Thoracic Surgery 2001, 20: 127-132. PMID: 11423285, DOI: 10.1016/s1010-7940(01)00765-5.Peer-Reviewed Original ResearchConceptsSingle-clamp techniqueCoronary artery bypassPostoperative strokeArtery bypassStroke preventionCerebrovascular accidentSide-biting aortic clampAdverse myocardial effectsCross-clamp timePostoperative adverse eventsPerioperative myocardial infarctionCoronary bypass operationsLogistic regression analysisEmbolic consequencesHospital mortalityAdverse eventsAortic clampMyocardial effectsBypass operationMyocardial infarctionMyocardial protectionClinical practiceClamp techniqueSecond surgeonStroke
2000
Effect of left ventricular volume on results of coronary artery bypass grafting
Kim R, Ugurlu B, Tereb D, Wackers F, Tellides G, Elefteriades J. Effect of left ventricular volume on results of coronary artery bypass grafting. The American Journal Of Cardiology 2000, 86: 1261-1264. PMID: 11090805, DOI: 10.1016/s0002-9149(00)01216-9.Peer-Reviewed Original ResearchConceptsCoronary artery bypassArtery bypassSignificant left ventricular dilationLeft ventricular dilationLV chamber sizeLV ejection fractionMedium-term survivalSurgical revascularizationAngina symptomsEjection fractionIschemic cardiomyopathyLV dilationVentricular dilationVentricular sizeVentricular volumePatientsSignificant reductionBypassChamber sizeDilationRevascularizationCardiomyopathySymptomsCoronary artery bypass for advanced left ventricular dysfunction
Elefteriades J, Tellides G, Samady H, Yepremyan M, Darr U, Wackers F, Zaret B. Coronary artery bypass for advanced left ventricular dysfunction. Developments In Cardiovascular Medicine 2000, 225: 15-31. DOI: 10.1007/978-0-585-29191-8_2.Peer-Reviewed Original ResearchAdvanced left ventricular dysfunctionLeft ventricular dysfunctionCoronary artery bypassVentricular dysfunctionArtery bypassSuch patientsCoronary artery bypass surgeryArtery bypass surgeryLarge multicenter trialsOpen heart surgeryCoronary revascularizationBypass surgeryMulticenter trialHeart surgeryRisk of operationPatientsDysfunctionBypassInexorable deteriorationCABGSurgeryLongevity benefitsScientific evaluationRevascularizationCardiologists
1998
Topical Hypothermia: Ineffective and Deleterious as Adjunct to Cardioplegia for Myocardial Protection
Nikas D, Ramadan F, Elefteriades J. Topical Hypothermia: Ineffective and Deleterious as Adjunct to Cardioplegia for Myocardial Protection. The Annals Of Thoracic Surgery 1998, 65: 28-31. PMID: 9456090, DOI: 10.1016/s0003-4975(97)01261-7.Peer-Reviewed Original ResearchConceptsCold blood cardioplegiaFirst postoperative dayTopical hypothermiaPostoperative dayPulmonary complicationsDiaphragmatic paralysisSystemic hypothermiaBlood cardioplegiaGroup AGroup BIced slushMyocardial protectionIntermittent cold blood cardioplegiaGroup B. Group AAdditional cardioprotective benefitNonrandomized consecutive patientsPhrenic nerve paralysisPostoperative cardiac morbidityCoronary artery bypassLow cardiac outputPerioperative myocardial infarctionCoronary bypass patientsB. Group ASignificant differencesInotrope useShould Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting?
Mehta I, Weinberg J, Jones M, Tellides G, Kopf G, Shaw R, Zaret B, Elefteriades J. Should Angiographically Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo Coronary Artery Bypass Grafting? The Annals Of Thoracic Surgery 1998, 65: 17-23. PMID: 9456088, DOI: 10.1016/s0003-4975(97)01192-2.Peer-Reviewed Original ResearchConceptsSaphenous vein graftsVein graftsRedo CABGDisease-free graftsNR groupRedo Coronary Artery Bypass GraftingR groupCoronary Artery Bypass GraftingRedo coronary artery bypassGood late survivalArtery Bypass GraftingCoronary artery bypassLate myocardial infarctionFirst CABGRecurrent anginaRedo revascularizationArtery bypassBypass GraftingOperative mortalitySurgical mortalityAngiographic evaluationCardiac hospitalizationConsecutive patientsNew stenosisRandomized study
1997
Results of Coronary Artery Bypass Grafting by a Single Surgeon Patients With Left Ventricular Ejection Fractions ≤30%
Elefteriades J, Morales D, Gradel C, Tollis G, Levi E, Zaret B. Results of Coronary Artery Bypass Grafting by a Single Surgeon Patients With Left Ventricular Ejection Fractions ≤30%. The American Journal Of Cardiology 1997, 79: 1573-1578. PMID: 9202343, DOI: 10.1016/s0002-9149(97)00201-4.Peer-Reviewed Original ResearchConceptsAdvanced LV dysfunctionInternal mammary arteryCoronary artery diseaseEjection fractionLV dysfunctionMammary arteryArtery diseaseCongestive heart failure classSevere left ventricular dysfunctionCoronary Artery Bypass GraftingBetter long-term survivalHeart failure classSingle surgeon's patientsArtery Bypass GraftingCoronary artery bypassHigh operative riskLeft ventricular dysfunctionSevere ventricular arrhythmiasLV ejection fractionVentricular ejection fractionUse of CABGLong-term survivalQuality of lifeAngina classArtery bypass
1993
Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state
Elefteriades J, Tolis G, Levi E, Mills L, Zaret B. Coronary artery bypass grafting in severe left ventricular dysfunction: Excellent survival with improved ejection fraction and functional state. Journal Of The American College Of Cardiology 1993, 22: 1411-1417. PMID: 8227799, DOI: 10.1016/0735-1097(93)90551-b.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdultAgedAged, 80 and overCause of DeathCoronary Artery BypassDefibrillators, ImplantableFemaleFollow-Up StudiesHeart DiseasesHospital MortalityHumansIntra-Aortic Balloon PumpingMaleMammary ArteriesMiddle AgedPrognosisQuality of LifeSeverity of Illness IndexStroke VolumeSurvival RateVentricular Function, LeftConceptsCoronary Artery Bypass GraftingArtery Bypass GraftingCoronary artery bypassSevere left ventricular dysfunctionLeft ventricular ejection fractionInternal mammary arteryLeft ventricular dysfunctionVentricular ejection fractionEjection fractionArtery bypassVentricular dysfunctionBypass GraftingMammary arteryMortality rateCanadian Cardiovascular Society angina classCongestive heart failure classGood medium-term survivalAdvanced ischemic cardiomyopathyAdvanced ventricular dysfunctionHeart failure classImproved ejection fractionHospital mortality rateCongestive heart failureIntraaortic balloon pumpSignificant ventricular arrhythmiasLinear left ventricular aneurysmectomy: Modern imaging studies reveal improved morphology and function
Elefteriades J, Solomon L, Salazar A, Batsford W, Baldwin J, Kopf G. Linear left ventricular aneurysmectomy: Modern imaging studies reveal improved morphology and function. The Annals Of Thoracic Surgery 1993, 56: 242-252. PMID: 8347005, DOI: 10.1016/0003-4975(93)91154-f.Peer-Reviewed Original ResearchConceptsCoronary artery bypassIntraoperative transesophageal echocardiographyArtery bypassVentricular aneurysmectomyTransesophageal echocardiographyConcomitant coronary artery bypassCongestive heart failure classFrank congestive heart failureHeart failure classActuarial survival rateHospital mortality rateCongestive heart failureWall motion scoreMean wall motion scoreModern imaging studiesMagnetic resonance imagingAcquisition scanningAnginal classValve replacementConsecutive patientsEjection fractionHeart failureVentricular functionEndocardial resectionVentricular morphologyTransesophageal two-dimensional echocardiographic analysis of right ventricular systolic performance indices during coronary artery bypass grafting
Rafferty T, Durkin M, Harris S, Elefteriades J, Hines R, Prokop E, O'Connor T. Transesophageal two-dimensional echocardiographic analysis of right ventricular systolic performance indices during coronary artery bypass grafting. Journal Of Cardiothoracic And Vascular Anesthesia 1993, 7: 160-166. PMID: 8477020, DOI: 10.1016/1053-0770(93)90210-c.Peer-Reviewed Original ResearchConceptsEnd-diastolic volume indexPulmonary artery pressureEnd-diastolic pressureCardiopulmonary bypassCardiac indexRV end-diastolic volume indexSignificant right coronary artery diseaseCoronary artery bypass surgeryRight coronary artery diseaseRV end-diastolic pressurePost-CPB valuesArtery bypass surgeryCoronary artery bypassCoronary artery diseaseMin/m2Two-dimensional echocardiographic analysisML/m2Inotropic supportIntraoperative courseArtery bypassArtery pressureBypass surgeryNitroglycerin infusionArtery diseaseEjection fraction
1990
Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias
Elefteriades J, Biblo L, Batsford W, Rosenfeld L, Henthorn R, Carlson M, Waldo A, Hsu J, Geha A. Evolving patterns in the surgical treatment of malignant ventricular tachyarrhythmias. The Annals Of Thoracic Surgery 1990, 49: 94-100. PMID: 2297279, DOI: 10.1016/0003-4975(90)90362-a.Peer-Reviewed Original ResearchConceptsAutomatic implantable cardioverter defibrillatorResection groupThirty-day mortalityCoronary artery bypassMalignant ventricular tachyarrhythmiasIntractable ventricular arrhythmiasImplantable cardioverter defibrillatorAICD placementArtery bypassSurgical treatmentEndocardial resectionVentricular arrhythmiasVentricular tachyarrhythmiasAntiarrhythmic agentsSudden deathCardioverter defibrillatorResectionMortality figuresPatientsEffective interventionsGreatest overall benefitSurvivalGroupOverall benefitValuable alternative
1988
Recovery of severe ischemic ventricular dysfunction after coronary artery bypass grafting
Brill D, Deckelbaum L, Remetz M, Soufer R, Elefteriades J, Zaret B. Recovery of severe ischemic ventricular dysfunction after coronary artery bypass grafting. The American Journal Of Cardiology 1988, 61: 650-651. PMID: 3257840, DOI: 10.1016/0002-9149(88)90784-9.Peer-Reviewed Original ResearchConceptsWall motion abnormalitiesVentricular dysfunctionLeft ventricularMotion abnormalitiesReversible wall motion abnormalitiesSevere coronary artery diseaseVentricular wall motion abnormalitiesIschemic ventricular dysfunctionReversible ventricular dysfunctionCoronary artery bypassCoronary artery diseasePeriod of ischemiaArtery bypassIschemic dysfunctionArtery diseaseHibernating myocardiumMyocardial infarctionMyocardial scarDysfunctionFibrous tissueRecent evidencePatientsComplete reversalAbnormalitiesRevascularization