2022
The Genetics of Inheritable Aortic Diseases
Kalyanasundaram A, Elefteriades J. The Genetics of Inheritable Aortic Diseases. Current Cardiovascular Risk Reports 2022, 16: 13-24. DOI: 10.1007/s12170-022-00687-x.Peer-Reviewed Original ResearchAbdominal aortic aneurysmRisk factorsAortic diseaseAortic aneurysmPatient outcomesGene variantsTraditional cardiovascular risk factorsBetter long-term survivalCV risk factorsDevelopment of TAADCardiovascular risk factorsBetter patient outcomesLong-term survivalGeneral risk factorsPurpose of ReviewOverTGF-β pathwayEarly surgeryLipid metabolism pathwaysDefinitive treatmentAneurysmal diseaseAortic diameterProphylactic surgeryAggressive casesPatient-specific guidelinesAortic wall
2021
Simple Hepatic Cysts as Markers of Thoracic Aortic Disease
C K, BA Z, MA Z, J B, J E. Simple Hepatic Cysts as Markers of Thoracic Aortic Disease. Journal Of Disease Markers 2021, 6 DOI: 10.26420/jdismarkers.2021.1043.Peer-Reviewed Original ResearchThoracic aortic diseaseSimple hepatic cystsBovine aortic archBicuspid aortic valveSimple renal cystsPositive family historyMost patientsAortic diseaseHepatic cystsRetrospective studyAortic aneurysmAortic archAortic valveClinical markersHospital patientsFamily historyRenal cystsTAD patientsControl groupPatientsAneurysmsPrevalenceCystsDiseaseClamp Above the Left Subclavian Artery
Elefteriades J, Ziganshin B. Clamp Above the Left Subclavian Artery. 2021, 71-72. DOI: 10.1007/978-3-030-78877-3_25.Peer-Reviewed Original Research
2019
Mechanics of the Thoracic Aortic Wall
Ziganshin B, Elefteriades J. Mechanics of the Thoracic Aortic Wall. 2019, 149-162. DOI: 10.1007/978-3-7091-4874-7_10.Peer-Reviewed Original Research
2018
Genetic testing to modulate when to operate in thoracic aortic disease
Kostiuk V, Brownstein A, Ziganshin B, Elefteriades J. Genetic testing to modulate when to operate in thoracic aortic disease. Journal Of Visualized Surgery 2018, 4: 193-193. DOI: 10.21037/jovs.2018.07.14.Peer-Reviewed Original ResearchMolecular geneticsThoracic aortic aneurysmSurgical treatment optionsNon-syndromic thoracic aortic aneurysmsMolecular profilingSmooth muscle cell functionFamilial thoracic aortic aneurysmsMultiple genesSpecific genesMuscle cell functionTAA patientsTreatment optionsExtracellular matrixCell functionThoracic aortic diseaseGenesPositive family historyGeneticsProfilingTAA developmentAortic diseaseAortic aneurysmCurrent classificationDisease progressionFamily historyTime to Move to Earlier Intervention for Thoracic Aortic Aneurysm?
Gryaznov A, Ziganshin B, Elefteriades J. Time to Move to Earlier Intervention for Thoracic Aortic Aneurysm? Structural Heart 2018, 2: 10-22. DOI: 10.1080/24748706.2017.1404664.Peer-Reviewed Original ResearchThoracic aortic aneurysmBody surface areaAortic aneurysmMost life-threatening complicationsAortic growth rateEarly prophylactic interventionAcute aortic dissectionLife-threatening complicationsPatient/yearProphylactic surgical interventionSpecific genetic aberrationsAortic dissectionAortic sizeAortic diseaseCurrent gold standardSurgical interventionPatient heightProphylactic interventionsThoracic aortaAneurysm diseaseCommon causeFamily historyEarly diagnosisEarly interventionGenetic aberrationsChapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms
Findlay R, Thompson O, Ziganshin B, Elefteriades J. Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms. 2018, 107-118. DOI: 10.1016/b978-0-12-809979-7.00010-9.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmAortic diseaseGiant cell arteritisAortic arch abnormalitiesBicuspid aortic valveThoracic aortic diseaseAbdominal aortic aneurysmConnective tissue disordersCell arteritisClinical findingsHigh morbidityAortic valveIncidental findingArch abnormalitiesClinical markersFamily historyTissue disordersRenal cystsTAA developmentAneurysmsIntracranial aneurysmsEarly detectionDiseasePatientsChapter 3 Histology of Aortic Disease and Progression of Aortic Dissection From Acute to Chronic
Zafar M, Peterss S, Ziganshin B, Elefteriades J. Chapter 3 Histology of Aortic Disease and Progression of Aortic Dissection From Acute to Chronic. 2018, 41-59. DOI: 10.1016/b978-0-12-809979-7.00003-1.Peer-Reviewed Original ResearchChronic stateUncomplicated acute type B dissectionAcute type B dissectionAcute Stanford typeType B dissectionEarly surgical interventionTreatment of choiceChronic dissectionB dissectionStanford typeAortic dissectionMedical therapyAortic diseaseSurgical interventionDissectionAortaTemporal courseHistologyMorphological changesAcuteChronicHistopathologyTherapyDiseaseProgression
2017
Mechanisms of Disease and Natural History
Ziganshin B, Elefteriades J. Mechanisms of Disease and Natural History. 2017, 19-43. DOI: 10.1007/978-3-319-15192-2_2.Peer-Reviewed Original ResearchAortic diseaseNatural historyEndovascular treatment optionsThoracic aortic diseaseClassic open surgeryDiseased aortic wallEvidence-based criteriaMechanisms of diseaseAortic pathologyAortic ruptureLethal complicationOpen surgeryProphylactic treatmentEndovascular interventionTreatment optionsIndividual patientsAortic wallPersonalized managementMechanisms of developmentDiseasePatientsSuch treatmentTreatmentCurrent understandingComplications
2013
Thoracic Aortic Disease
Ziganshin B, Elefteriades J. Thoracic Aortic Disease. 2013, 331-353. DOI: 10.1007/978-1-4471-4441-0_23.Peer-Reviewed Original ResearchThoracic aortic diseaseAortic aneurysmAortic diseaseAortic growth rateAge 65 yearsThoracic aortic aneurysmCurrent diagnostic approachesDate management strategiesDevastating complicationAortic dissectionIndolent processAortic pathologyPathognomonic symptomsFirst manifestationRecent guidelinesCommon causeAneurysmsDiagnostic approachDisease controlDiseaseSilent natureFamilial inheritanceVirulent diseaseTimely detectionGenetic diseases
1999
Management of descending aortic dissection
Elefteriades J, Lovoulos C, Coady M, Tellides G, Kopf G, Rizzo J. Management of descending aortic dissection. The Annals Of Thoracic Surgery 1999, 67: 2002-2005. PMID: 10391358, DOI: 10.1016/s0003-4975(99)00428-2.Peer-Reviewed Original ResearchConceptsThoracic aortic diseaseAortic replacementAortic dissectionAortic diseaseVascular occlusionCategory of patientsEarly hospital courseTime of dissectionParaplegia rateAcute dissectionHospital coursePostoperative deathsAcute expansionPatient demographicsConsecutive patientsMultiple complicationsBenign courseMedical managementSpecific complicationsSurgical interventionClinical recordsAortic aneurysmComplicated dissectionFenestration procedureTherapy variesFamilial Patterns of Thoracic Aortic Aneurysms
Coady M, Davies R, Roberts M, Goldstein L, Rogalski M, Rizzo J, Hammond G, Kopf G, Elefteriades J. Familial Patterns of Thoracic Aortic Aneurysms. JAMA Surgery 1999, 134: 361-367. PMID: 10199307, DOI: 10.1001/archsurg.134.4.361.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmSporadic thoracic aortic aneurysmConcomitant aortic dissectionAortic dissectionAortic aneurysmMarfan syndromeAortic diseaseAutosomal recessive modeFamilial patternMean ageFamily historyRecessive modeCollagen vascular disordersTime of diagnosisThoracic aortic diseaseGenetic factorsNew risk factorsFamily pedigreeConcomitant diseasesRetrospective reviewAortic sizeUniversity HospitalRisk factorsVascular disordersAutosomal dominant mode