2023
The natural history of aortic root aneurysms
Ziganshin B, Kargin N, Zafar M, Elefteriades J. The natural history of aortic root aneurysms. Annals Of Cardiothoracic Surgery 2023, 12: 21324-21224. PMID: 37304695, PMCID: PMC10248916, DOI: 10.21037/acs-2023-avs1-20.Peer-Reviewed Original ResearchFate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University
Wu J, Zafar M, Liu Y, Chen J, Li Y, Ziganshin B, Ellauzi H, Mukherjee S, Rizzo J, Elefteriades J. Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University. European Heart Journal 2023, 44: 4579-4588. PMID: 36994934, DOI: 10.1093/eurheartj/ehad148.Peer-Reviewed Original ResearchConceptsAdverse aortic eventsThoracic aortic aneurysmAortic sizeAortic aneurysmCox regressionAortic growthRisk factorsSignificant independent risk factorsMultivariable Cox regressionIndependent risk factorCohort of patientsUnivariable Cox regressionSignificant protective factorAortic deathATAA patientsAortic eventsPrimary endpointSurgical interventionThree-decade experienceNatural historyYearly riskProtective factorsAneurysmsPatientsIntervention criteriaFull calcium jacket: Conservative management of a traumatic aortic injury
Tripathi R, Ellauzi H, Zafar M, Ziganshin B, Elefteriades J. Full calcium jacket: Conservative management of a traumatic aortic injury. Journal Of Vascular Surgery Cases And Innovative Techniques 2023, 9: 101132. PMID: 37139352, PMCID: PMC10149390, DOI: 10.1016/j.jvscit.2023.101132.Peer-Reviewed Original ResearchKIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection
Velasco J, Li Y, Ziganshin B, Zafar M, Rizzo J, Ma D, Zang H, Kalyanasundaram A, Elefteriades J. KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. Genes 2023, 14: 252. PMID: 36833179, PMCID: PMC9956195, DOI: 10.3390/genes14020252.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic dissectionOdds ratioVariant statusArg allele carriersThoracic aortic dissectionOccurrence of ADAortic sizeArg alleleMarked adverse impactTAA patientsAortic aneurysmClinical assessmentSurgical decisionAllele carriersIncrease riskVariant patientsArg carriersPilot studyDissectionImportant intracellular functionsConfirmatory findingsPatientsAneurysmsPresent study
2021
Ascending Aneurysms in Heart Transplant Patients A Rare Opportunity to Assess Heredity Versus Biological Environment
Anis O, Kopf G, Ziganshin B, Zafar M, Tranquilli M, Sieller R, Elefteriades J. Ascending Aneurysms in Heart Transplant Patients A Rare Opportunity to Assess Heredity Versus Biological Environment. JACC Case Reports 2021, 3: 1685-1689. PMID: 34766019, PMCID: PMC8571777, DOI: 10.1016/j.jaccas.2021.07.010.Peer-Reviewed Original ResearchSimple Hepatic Cysts as Markers of Thoracic Aortic Disease
C K, BA Z, MA Z, J B, J E. Simple Hepatic Cysts as Markers of Thoracic Aortic Disease. Journal Of Disease Markers 2021, 6 DOI: 10.26420/jdismarkers.2021.1043.Peer-Reviewed Original ResearchThoracic aortic diseaseSimple hepatic cystsBovine aortic archBicuspid aortic valveSimple renal cystsPositive family historyMost patientsAortic diseaseHepatic cystsRetrospective studyAortic aneurysmAortic archAortic valveClinical markersHospital patientsFamily historyRenal cystsTAD patientsControl groupPatientsAneurysmsPrevalenceCystsDiseaseAdherence of Aortic Aneurysm to Chest Wall
Elefteriades J, Ziganshin B. Adherence of Aortic Aneurysm to Chest Wall. 2021, 115-116. DOI: 10.1007/978-3-030-78877-3_42.Peer-Reviewed Original ResearchStand-Alone Elephant Trunk Procedure
Elefteriades J, Ziganshin B. Stand-Alone Elephant Trunk Procedure. 2021, 185-186. DOI: 10.1007/978-3-030-78877-3_59.Peer-Reviewed Original ResearchPulmonary Artery Aneurysms
Elefteriades J, Ziganshin B. Pulmonary Artery Aneurysms. 2021, 285-287. DOI: 10.1007/978-3-030-78877-3_69.Peer-Reviewed Original Research
2020
Aortic Arch Aneurysms
Imran M, Zafar M, Chkhikvadze T, Ziganshin B, Elefteriades J. Aortic Arch Aneurysms. 2020, 529-544. DOI: 10.1007/978-3-030-24174-2_57.Peer-Reviewed Original Research
2018
Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms
Findlay R, Thompson O, Ziganshin B, Elefteriades J. Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms. 2018, 107-118. DOI: 10.1016/b978-0-12-809979-7.00010-9.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmAortic diseaseGiant cell arteritisAortic arch abnormalitiesBicuspid aortic valveThoracic aortic diseaseAbdominal aortic aneurysmConnective tissue disordersCell arteritisClinical findingsHigh morbidityAortic valveIncidental findingArch abnormalitiesClinical markersFamily historyTissue disordersRenal cystsTAA developmentAneurysmsIntracranial aneurysmsEarly detectionDiseasePatientsAortic Aneurysm
Singh M, Ziganshin B, Elefteriades J. Aortic Aneurysm. 2018, 123-142. DOI: 10.1016/b978-0-12-809657-4.99690-x.Peer-Reviewed Original ResearchAortic Aneurysm
Singh M, Ziganshin B, Elefteriades J. Aortic Aneurysm. 2018 DOI: 10.1016/b978-0-12-801238-3.99690-9.Peer-Reviewed Original Research
2016
Advanced Glycation End Products and its Soluble Receptors in the Pathogenesis of Thoracic Aortic Aneurysm
Prasad K, Sarkar A, Zafar M, Shoker A, Moselhi H, Tranquilli M, Ziganshin B, Elefteriades J. Advanced Glycation End Products and its Soluble Receptors in the Pathogenesis of Thoracic Aortic Aneurysm. Aorta 2016, 4 DOI: 10.12945/j.aorta.2016.15.018.Peer-Reviewed Original Research
2013
Thoracic Aortic Disease
Ziganshin B, Elefteriades J. Thoracic Aortic Disease. 2013, 331-353. DOI: 10.1007/978-1-4471-4441-0_23.Peer-Reviewed Original ResearchThoracic aortic diseaseAortic aneurysmAortic diseaseAortic growth rateAge 65 yearsThoracic aortic aneurysmCurrent diagnostic approachesDate management strategiesDevastating complicationAortic dissectionIndolent processAortic pathologyPathognomonic symptomsFirst manifestationRecent guidelinesCommon causeAneurysmsDiagnostic approachDisease controlDiseaseSilent natureFamilial inheritanceVirulent diseaseTimely detectionGenetic diseases
2012
Respecting Symptoms in Thoracic Aortic Aneurysm Management: A Case of Symptomatic Necrotizing Granulomatous Aortitis
Kuzmik G, Sang A, Cai G, Tranquilli M, Elefteriades J. Respecting Symptoms in Thoracic Aortic Aneurysm Management: A Case of Symptomatic Necrotizing Granulomatous Aortitis. International Journal Of Angiology 2012, 21: 151-154. PMID: 23997559, PMCID: PMC3578625, DOI: 10.1055/s-0032-1315632.Peer-Reviewed Case Reports and Technical NotesAortic aneurysm managementComputed tomography angiographyThoracic aortic aneurysmInterventional criteriaChest painAortic pathologyAortic ruptureNoninfectious etiologiesRadiographic evidenceUnclear etiologyAortic aneurysmTomography angiographyGranulomatous aortitisSurgical decisionAneurysm managementOperating roomAortitisIrregular contoursAneurysmsAortaEtiologySymptomsImminent riskRupturePainCAROTID INTIMA MEDIA THICKNESS CONFIRMS PROTECTION AGAINST ATHEROSCLEROSIS IN PATIENTS WITH ASCENDING AORTIC ANEURYSM
Hung A, Zafar M, Tranquilli M, Scoutt L, Elefteriades J. CAROTID INTIMA MEDIA THICKNESS CONFIRMS PROTECTION AGAINST ATHEROSCLEROSIS IN PATIENTS WITH ASCENDING AORTIC ANEURYSM. Journal Of The American College Of Cardiology 2012, 59: e1769. DOI: 10.1016/s0735-1097(12)61770-7.Peer-Reviewed Original Research
2011
Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms
Stein L, Elefteriades J. Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms. 2011, 25-32. DOI: 10.1007/978-88-470-1857-0_3.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmThoraco-abdominal aortic aneurysmChronic obstructive pulmonary diseaseObstructive pulmonary diseaseSmooth muscle cellsTAAA rupturePulmonary diseaseTertiary centerAortic diameterTAAANatural historyAneurysm growthMuscle cellsOptimal timingAneurysmsPresent unique challengesRiskBetter identificationRupture increasesHypertensionSmokingPatientsDerangementUnique challenges
2008
Natural History: Evidence‐Based Indications for Operation
Elefteriades J. Natural History: Evidence‐Based Indications for Operation. 2008, 19-27. DOI: 10.1002/9781444300512.ch3.Peer-Reviewed Original ResearchAneurysmal thoracic aortaThoracic aorta ruptureThoracic aortaAortic eventsAortic ulcerIntramural hematomaProphylactic resectionMedical managementAneurysm patientsAorta ruptureAortic archLethal diseaseImpact of dissectionPatient sizeEvidence-based indicationsSize criteriaAortaNatural historyHematomaResectionUlcersPatientsAneurysmsThoracicDisease
2006
Familial Thoracic Aortic Aneurysms and Dissections—Incidence, Modes of Inheritance, and Phenotypic Patterns
Albornoz G, Coady MA, Roberts M, Davies RR, Tranquilli M, Rizzo JA, Elefteriades JA. Familial Thoracic Aortic Aneurysms and Dissections—Incidence, Modes of Inheritance, and Phenotypic Patterns. The Annals Of Thoracic Surgery 2006, 82: 1400-1405. PMID: 16996941, DOI: 10.1016/j.athoracsur.2006.04.098.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAbdominal aortic aneurysmFamilial thoracic aortic aneurysmsAortic aneurysmMarfan syndromeAortic growth rateNon-Marfan patientsIncidence of hypertensionAggressive clinical entityPredominant inheritance patternSporadic groupMarfan groupStudy patientsCerebral circulationClinical entityThoracic aortaAbdominal aortaInheritance patternMFS groupMFS patientsTAA groupLarge cohortAneurysm sitePatientsAneurysms