2022
The Genetics of Inheritable Aortic Diseases
Kalyanasundaram A, Elefteriades J. The Genetics of Inheritable Aortic Diseases. Current Cardiovascular Risk Reports 2022, 16: 13-24. DOI: 10.1007/s12170-022-00687-x.Peer-Reviewed Original ResearchAbdominal aortic aneurysmRisk factorsAortic diseaseAortic aneurysmPatient outcomesGene variantsTraditional cardiovascular risk factorsBetter long-term survivalCV risk factorsDevelopment of TAADCardiovascular risk factorsBetter patient outcomesLong-term survivalGeneral risk factorsPurpose of ReviewOverTGF-β pathwayEarly surgeryLipid metabolism pathwaysDefinitive treatmentAneurysmal diseaseAortic diameterProphylactic surgeryAggressive casesPatient-specific guidelinesAortic wall
2018
Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms
Findlay R, Thompson O, Ziganshin B, Elefteriades J. Chapter 10 Guilt by Association Paradigm for Detection of Silent Aortic Aneurysms. 2018, 107-118. DOI: 10.1016/b978-0-12-809979-7.00010-9.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmAortic diseaseGiant cell arteritisAortic arch abnormalitiesBicuspid aortic valveThoracic aortic diseaseAbdominal aortic aneurysmConnective tissue disordersCell arteritisClinical findingsHigh morbidityAortic valveIncidental findingArch abnormalitiesClinical markersFamily historyTissue disordersRenal cystsTAA developmentAneurysmsIntracranial aneurysmsEarly detectionDiseasePatients
2006
Familial Thoracic Aortic Aneurysms and Dissections—Incidence, Modes of Inheritance, and Phenotypic Patterns
Albornoz G, Coady MA, Roberts M, Davies RR, Tranquilli M, Rizzo JA, Elefteriades JA. Familial Thoracic Aortic Aneurysms and Dissections—Incidence, Modes of Inheritance, and Phenotypic Patterns. The Annals Of Thoracic Surgery 2006, 82: 1400-1405. PMID: 16996941, DOI: 10.1016/j.athoracsur.2006.04.098.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAbdominal aortic aneurysmFamilial thoracic aortic aneurysmsAortic aneurysmMarfan syndromeAortic growth rateNon-Marfan patientsIncidence of hypertensionAggressive clinical entityPredominant inheritance patternSporadic groupMarfan groupStudy patientsCerebral circulationClinical entityThoracic aortaAbdominal aortaInheritance patternMFS groupMFS patientsTAA groupLarge cohortAneurysm sitePatientsAneurysms