2023
Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University
Wu J, Zafar M, Liu Y, Chen J, Li Y, Ziganshin B, Ellauzi H, Mukherjee S, Rizzo J, Elefteriades J. Fate of the unoperated ascending thoracic aortic aneurysm: three-decade experience from the Aortic Institute at Yale University. European Heart Journal 2023, 44: 4579-4588. PMID: 36994934, DOI: 10.1093/eurheartj/ehad148.Peer-Reviewed Original ResearchConceptsAdverse aortic eventsThoracic aortic aneurysmAortic sizeAortic aneurysmCox regressionAortic growthRisk factorsSignificant independent risk factorsMultivariable Cox regressionIndependent risk factorCohort of patientsUnivariable Cox regressionSignificant protective factorAortic deathATAA patientsAortic eventsPrimary endpointSurgical interventionThree-decade experienceNatural historyYearly riskProtective factorsAneurysmsPatientsIntervention criteria
2021
A probabilistic and anisotropic failure metric for ascending thoracic aortic aneurysm risk assessment
Liu M, Liang L, Zou Q, Ismail Y, Lou X, Iannucci G, Chen E, Leshnower B, Elefteriades J, Sun W. A probabilistic and anisotropic failure metric for ascending thoracic aortic aneurysm risk assessment. Journal Of The Mechanics And Physics Of Solids 2021, 155: 104539. DOI: 10.1016/j.jmps.2021.104539.Peer-Reviewed Original ResearchATAA patientsAortic wallAortic tissue samplesThoracic aortic aneurysmAortic aneurysmAneurysm rupturePatientsRisk assessmentTissue samplesCharacteristic curveFailure metricsTsai-Hill failure criterionCT imagesRiskTensile failure testsMaximum principal stressRupture risk assessmentPrevious studiesAssessment