2010
Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis
Sridhar G, Masho SW, Adera T, Ramakrishnan V, Roberts JD. Do African American Men Have Lower Survival From Prostate Cancer Compared With White Men? A Meta-analysis. American Journal Of Men's Health 2010, 4: 189-206. PMID: 20483872, DOI: 10.1177/1557988309353934.Peer-Reviewed Original ResearchConceptsProstate cancer-specific survivalCancer-specific survivalProstate cancerAfrican American menWhite menCancer-related mortalityAmerican menUnadjusted studiesCause mortalityMeta-AnalysisSystematic reviewCancerSurvivalRacial differencesMenSignificant differencesMortalityLower survivalDifferences
2000
Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034.
McLeod HL, Cassidy J, Powrie RH, Priest DG, Zorbas MA, Synold TW, Shibata S, Spicer D, Bissett D, Pithavala YK, Collier MA, Paradiso LJ, Roberts JD. Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034. Clinical Cancer Research 2000, 6: 2677-84. PMID: 10914709.Peer-Reviewed Original ResearchConceptsGlycinamide ribonucleotide formyltransferaseCourse 1Systemic clearanceGrade III/IV toxicityGrade II toxicityMin/m2Rapid systemic clearanceVolume of distributionEvaluable patientsSystemic exposurePharmacodynamic evaluationClinical centersBolus injectionPharmacokinetic approachBlood samplesPatient toxicityPatientsElimination patternReproducible ELISAAG2034Course 3Phase IAnticancer agentsPurine synthesis pathwayDe novo purine synthesis pathway