2021
The prognostic value of heart rate at discharge in acute decompensation of heart failure with reduced ejection fraction
Bahouth F, Elias A, Ghersin I, Khoury E, Bar O, Sholy H, Khoury J, Azzam Z. The prognostic value of heart rate at discharge in acute decompensation of heart failure with reduced ejection fraction. ESC Heart Failure 2021, 9: 585-594. PMID: 34821080, PMCID: PMC8788061, DOI: 10.1002/ehf2.13710.Peer-Reviewed Original ResearchConceptsReduced ejection fractionHeart rateHeart failureHazard ratioEjection fractionPrognostic valueTarget doseMortality rateChronic stable heart failureBeta-blocker dosageHeart failure settingAdjusted hazard ratioStable heart failureDay mortality rateSingle-center studyRetrospective observational studyYear mortality rateElevated heart rateLower heart rateHR 70Acute decompensationCause mortalityLaboratory variablesYear mortalityCox regression
2019
Blood urea nitrogen variation upon admission and at discharge in patients with heart failure
Khoury J, Bahouth F, Stabholz Y, Elias A, Mashiach T, Aronson D, Azzam Z. Blood urea nitrogen variation upon admission and at discharge in patients with heart failure. ESC Heart Failure 2019, 6: 809-816. PMID: 31199082, PMCID: PMC6676277, DOI: 10.1002/ehf2.12471.Peer-Reviewed Original ResearchConceptsBlood urea nitrogenDay mortality rateHeart failureHigher BUN levelsPrognostic predictorBUN levelsMortality rateAcute decompensated heart failureDecompensated heart failureLong-term mortalityBrain natriuretic peptideGlomerular filtration rateShort-term mortalityLack of improvementBUN changeDay mortalityHospital stayCreatinine levelsFirst hospitalizationFirst admissionWorse prognosisMean ageNatriuretic peptidePrognostic valueRetrospective study
2018
Glycogenic hepatopathy
Khoury J, Zohar Y, Shehadeh N, Saadi T. Glycogenic hepatopathy. Hepatobiliary & Pancreatic Diseases International 2018, 17: 113-118. PMID: 29709217, DOI: 10.1016/j.hbpd.2018.02.006.Peer-Reviewed Original ResearchConceptsGlycogenic hepatopathyLiver biopsyLiver diseaseRight upper quadrant abdominal painUpper quadrant abdominal painEnd-stage liver diseaseNonalcoholic fatty liver diseaseUncontrolled diabetes mellitusQuadrant abdominal painFatty liver diseaseRoutine blood testsTight glycemic controlLiver glycogen accumulationPubMed database searchAbdominal painClinical responseElevated liverDiabetes mellitusGlycemic controlClinical presentationBlood testsPhysical examinationMedical historyNoninvasive testsLiver enzymes
2017
The prognostic value of brain natriuretic peptide (BNP) in non-cardiac patients with sepsis, ultra-long follow-up
Khoury J, Arow M, Elias A, Makhoul B, Berger G, Kaplan M, Mashiach T, Ismael-Badarneh R, Aronson D, Azzam Z. The prognostic value of brain natriuretic peptide (BNP) in non-cardiac patients with sepsis, ultra-long follow-up. Journal Of Critical Care 2017, 42: 117-122. PMID: 28719839, DOI: 10.1016/j.jcrc.2017.07.009.Peer-Reviewed Original ResearchConceptsBrain natriuretic peptideLong-term mortalityBNP levelsElevated brain natriuretic peptide levelsRole of BNPBrain natriuretic peptide levelsOrgan Failure Assessment scoreNatriuretic peptide levelsNon-cardiac patientsStrong independent predictorIncidence of morbidityLow-risk groupLong-term survivalMultivariate analysis modelHospital mortalityIndex hospitalizationCritical illnessHeart failureIndependent predictorsSeptic shockNatriuretic peptideOutcome predictorsPrognostic predictorPrognostic valueMultifactorial syndrome
2014
Alkaline phosphatase level change in patients with osteosarcoma: its role as a predictive factor of tumor necrosis and clinical outcome.
Khoury J, Ben-Arush M, Weintraub M, Waldman E, Futerman B, Vlodavsky E, Postovsky S. Alkaline phosphatase level change in patients with osteosarcoma: its role as a predictive factor of tumor necrosis and clinical outcome. Israel Medical Association Journal 2014, 16: 26-32. PMID: 24575501.Peer-Reviewed Original ResearchConceptsTumor necrosisBetter prognosisClinical outcomesPredictive factorsHistological responseBetter survivalSerum alkaline phosphatase levelsEvidence of diseaseSignificant predictive factorsAlkaline phosphatase levelsNeoadjuvant chemotherapyOverall survivalWorse survivalFemale patientsMedical filesOsteosarcoma patientsPatientsPhosphatase levelsSAP responseNecrosisFirst monthRespondersPredictive indicatorDiseaseSurvival