2024
Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease
Krishnamurti L, Liang J, He Z, Deng Y, Nallagatla V, Hamidi R, Flagg A, Shah N. Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease. Blood Advances 2024, 8: 1908-1919. PMID: 38324722, PMCID: PMC11021890, DOI: 10.1182/bloodadvances.2023010749.Peer-Reviewed Original ResearchHematopoietic cell transplantationSickle cell diseaseVaso-occlusive episodesPainful crisesCell transplantationPost-HCTGraft failureBefore HCTEvent-free survivalOverall survivalPain syndromePatient agePatient-centered outcomesAlternative donorsIncreased riskCell diseaseRisk factorsNatural historyPatientsLogistic regressionPainTransplantationSurvivalAgeAGVHDComparison of Outcomes of Hematopoietic Cell Transplantation (HCT) for Asymptomatic Patients with Sickle Cell Disease (SCD) and That of Propensity Matched Symptomatic Patients Undergoing HCT
Katoch D, Nallagatla V, Liang J, Deng Y, Krishnamurti L. Comparison of Outcomes of Hematopoietic Cell Transplantation (HCT) for Asymptomatic Patients with Sickle Cell Disease (SCD) and That of Propensity Matched Symptomatic Patients Undergoing HCT. Transplantation And Cellular Therapy 2024, 30: s65. DOI: 10.1016/j.jtct.2023.12.103.Peer-Reviewed Original ResearchHematopoietic cell transplantationOutcomes of hematopoietic cell transplantationSickle cell diseaseSymptomatic SCD patientsAsymptomatic patientsDonor typeSymptomatic patientsPost-HCTSCD patientsHematopoietic cell transplantation comorbidity indexPost-transplant lymphoproliferative disorderMedian follow-up periodComplication of sickle cell diseaseIncidence of aGVHDReduced intensity conditioningSickle cell disease patientsFollow-up periodPropensity-matched modelStandardized mean differenceSecondary malignanciesLymphoproliferative disordersCell transplantationGraft survivalPatient ageAssociated with group classificationRisk Factors for the Development of Non-Infectious Pulmonary Complications Post-Hematopoietic Cell Transplantation in Sickle Cell Disease
Nallagatla V, Deng Y, Liang J, Krishnamurti L. Risk Factors for the Development of Non-Infectious Pulmonary Complications Post-Hematopoietic Cell Transplantation in Sickle Cell Disease. Transplantation And Cellular Therapy 2024, 30: s67. DOI: 10.1016/j.jtct.2023.12.106.Peer-Reviewed Original ResearchNon-infectious pulmonary complicationsAcute respiratory distress syndromeIdiopathic pneumonia syndromeMatched unrelated donorsPost-HCTPulmonary complicationsMechanical ventilationHLA mismatchesRisk factorsUnrelated donorCenter for International Blood and Marrow Transplant Research (CIBMTR) registryIncreased riskAssociated with pulmonary complicationsTransplant-related risk factorsPost-hematopoietic cell transplantationComplications of HCTPost-HCT complicationsHistory of ACYear of transplantationRespiratory distress syndromeTransplant-related factorsMultivariate logistic regression modelMultivariate logistic regressionDisease-related factorsPneumonia syndromeIn‐person validation of the Ichthyosis Scoring System
Echeandia‐Francis C, Sun Q, Asch S, Bayart C, Benjamin L, Cipriano S, Craiglow B, Dyer J, Levy M, Lilly E, Newell B, Liang J, Gan G, Deng Y, Paller A, Choate K. In‐person validation of the Ichthyosis Scoring System. Pediatric Dermatology 2024, 41: 247-252. PMID: 38234066, DOI: 10.1111/pde.15508.Peer-Reviewed Original ResearchInterrater intraclass correlation coefficientsIntrarater reliabilityIn-personIntraclass correlation coefficientIn-person evaluationContent validityInterrater reliabilityHeterogeneous group of skin disordersGroup of skin disordersIntraraterMedical professionalsInterrater agreementErythema evaluationIchthyosis subtypesPhotographic evaluationErythema scoreInterraterErythemaQuantify severitySkin disordersClinical utilityIchthyosisScoring systemHeterogeneous groupCorrelation coefficient
2023
Risk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study
Raju R, Holder E, Dundas M, Liang J, Donham R. Risk of SARS‐CoV‐2 following joint and epidural corticosteroid injections: A retrospective study. Pain Practice 2023, 24: 472-482. PMID: 37994676, DOI: 10.1111/papr.13321.Peer-Reviewed Original ResearchPCR positivity ratesCharlson Comorbidity IndexInjection groupPositivity rateCS injectionsControl groupCorticosteroid injectionSevere comorbiditiesPolymerase chain reaction positivitySARS-CoV-2 PCREpidural corticosteroid injectionsRetrospective chart reviewTertiary care centerCohort of patientsSignificant disease burdenCoronavirus disease 2019 (COVID-19) pandemicSignificant higher rateSARS-CoV-2Disease 2019 pandemicMultivariate regression analysisComorbidity indexPatients 18Chart reviewRetrospective studyImmunosuppressive effects
2021
Gradient Descent and Newton's Method with Backtracking Line Search in Linear Regression
Liang J. Gradient Descent and Newton's Method with Backtracking Line Search in Linear Regression. 2021, 00: 394-397. DOI: 10.1109/cds52072.2021.00073.Peer-Reviewed Original ResearchBacktracking line searchLine searchNewton methodBacktracking line search methodLine search methodEfficiency of optimization algorithmsOptimization algorithmSupervised machine learningRegression problemIteration stepNewtonGradient descentExecution timeMachine learningRate alphaOptimal parameter valuesSearch methodParameter valuesAlgorithmLearningSearchIteration