2023
Outcomes of immunomodulator and advanced therapies for primary sclerosing cholangitis-associated inflammatory bowel disease
Sayed A, Assis D, Silveira M, Deng Y, Ciarleglio M, Gaidos J, Proctor D, Al-Bawardy B. Outcomes of immunomodulator and advanced therapies for primary sclerosing cholangitis-associated inflammatory bowel disease. European Journal Of Gastroenterology & Hepatology 2023, 35: 270-274. PMID: 36708297, DOI: 10.1097/meg.0000000000002510.Peer-Reviewed Original ResearchConceptsPrimary sclerosing cholangitisInflammatory bowel diseasePSC-IBDEndoscopic healingTherapy groupAdvanced therapiesClinical remissionBowel diseaseAcute ascending cholangitisRate of cholangitisSmall bowel involvementThird of patientsAscending cholangitisSclerosing cholangitisAdult patientsBowel involvementSecondary outcomesMedian agePrimary outcomeRetrospective studyHigh riskCholangitisPatientsTherapyLarger study
2022
A Practical Approach to IBD Care in the Pregnant Patient
Sahyoun L, Gaidos J. A Practical Approach to IBD Care in the Pregnant Patient. Current Gastroenterology Reports 2022, 24: 201-209. PMID: 36422770, DOI: 10.1007/s11894-022-00856-3.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseManagement of IBDPrior inflammatory bowel diseaseNew IBD therapiesNew biologic agentsPouch-anal anastomosisSimilar success ratesPurpose of ReviewAsIBD careIBD patientsIBD therapyActive diseaseDisease remissionFetal outcomesIBD treatmentPregnant patientsIBD populationPreconception counselingPregnancy outcomesBiologic agentsBowel diseasePeripartum periodMedication safetyPrevious guidelinesPregnancy
2020
Medication Adherence During Pregnancy in IBD: Compliance Avoids Complications
Gaidos JKJ, Kane SV. Medication Adherence During Pregnancy in IBD: Compliance Avoids Complications. Digestive Diseases And Sciences 2020, 66: 336-337. PMID: 32323073, DOI: 10.1007/s10620-020-06271-w.Peer-Reviewed Original ResearchIdentifying IBD Providers’ Knowledge Gaps Using a Prospective Web-based Survey
Malter L, Jain A, Cohen BL, Gaidos JKJ, Axisa L, Butterfield L, Rescola BJ, Sarode S, Ehrlich O, Cheifetz AS. Identifying IBD Providers’ Knowledge Gaps Using a Prospective Web-based Survey. Inflammatory Bowel Diseases 2020, 26: 1445-1450. PMID: 32100018, DOI: 10.1093/ibd/izaa032.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseAdvanced practice providersPractice providersManagement of patientsProspective web-based surveyMajority of providersMental health providersAdvance practice providersUse of biosimilarsGreatest educational needsMedical education hoursIBD knowledgeIBD providersIBD patientsMD/DODrug holidayElderly patientsPregnant patientsPrior malignancyAdult patientsBowel diseaseTreatment landscapePain managementColitis FoundationTherapy decisions
2019
The Incidence and Prevalence of Anxiety, Depression, and Post-traumatic Stress Disorder in a National Cohort of US Veterans With Inflammatory Bowel Disease
Thakur ER, Sansgiry S, Kramer JR, Waljee AK, Gaidos JK, Feagins LA, Govani SM, Dindo L, El-Serag HB, Hou JK. The Incidence and Prevalence of Anxiety, Depression, and Post-traumatic Stress Disorder in a National Cohort of US Veterans With Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2019, 26: 1423-1428. PMID: 31728520, PMCID: PMC7441098, DOI: 10.1093/ibd/izz280.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseasePrevalence of anxietyPosttraumatic stress disorderMental health problemsStress disorderBowel diseaseUS veteransIncidence rateChronicity of IBDHealth problemsAnnual incidence rateStress disorder diagnosisPosttraumatic stress disorder (PTSD) diagnosisPost-traumatic stress disorderPresence of anxietyIBD patientsStudy cohortNational cohortAnnual prevalenceDiagnosis incidenceDirect standardization methodGeneral populationPatientsPrior anxietyPrevalence
2018
Health Maintenance Documentation Improves for Veterans with IBD Using a Template in the Computerized Patient Record System
Valluru N, Kang L, Gaidos JKJ. Health Maintenance Documentation Improves for Veterans with IBD Using a Template in the Computerized Patient Record System. Digestive Diseases And Sciences 2018, 63: 1782-1786. PMID: 29736836, DOI: 10.1007/s10620-018-5093-5.Peer-Reviewed Original ResearchConceptsPreventive care measuresComputerized patient record systemCare measuresIBD patientsMedication usePreventive carePatient record systemBackgroundInflammatory bowel diseaseImmunosuppressive medication useRetrospective chart reviewRecord systemHPV vaccinationIBD careChart reviewIBD populationBowel diseasePreventable complicationsProvider documentationClinic notesPhysician performance measuresAimThe aimProvider compliancePatientsDemographic dataMcNemar test
2017
Sexuality, Fertility, and Pregnancy in Crohn's Disease
Gaidos J, Kane S. Sexuality, Fertility, and Pregnancy in Crohn's Disease. Gastroenterology Clinics Of North America 2017, 46: 531-546. PMID: 28838413, DOI: 10.1016/j.gtc.2017.05.007.Peer-Reviewed Original ResearchMeSH KeywordsCongenital AbnormalitiesCrohn DiseaseFemaleFertilityHumansImmunosuppressive AgentsInfant, Low Birth WeightInfant, Small for Gestational AgeInfertility, FemaleInfertility, MaleMaleMethotrexatePregnancyPregnancy ComplicationsPremature BirthRisk FactorsSexual HealthStillbirthTumor Necrosis Factor-alphaConceptsCrohn's diseaseAnti-tumor necrosis factor medicationsAdverse pregnancy outcomesInflammatory bowel diseaseActive diseaseQuiescent diseaseMedication regimenPregnancy outcomesBowel diseaseIntrauterine exposureGeneral populationLive vaccineSexual healthDrug concentrationsDiseasePregnancyMonthsOutcomesFertility rateRemissionMedicationsRegimenPatientsInfantsVaccineIncidence of and Predictors for Early Discontinuation of Biological Therapies in Veteran Patients with Inflammatory Bowel Disease
Feagins LA, Waljee A, Hou JK, Gu P, Kanjo S, Rudrapatna V, Cipher DJ, Govani S, Gaidos J. Incidence of and Predictors for Early Discontinuation of Biological Therapies in Veteran Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2017, 23: 1434-1439. PMID: 28570429, DOI: 10.1097/mib.0000000000001145.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseBiological therapyAdverse drug reactionsConcomitant thiopurinesPrimary nonresponseEarly discontinuationBowel diseaseDrug reactionsDiagnosis of IBDBiological agentsFirst biological agentRetrospective cohort studyInitiation of therapyCourse of therapyVA hospital systemIleocolonic diseaseVA cohortCohort studyVeteran patientsMedical recordsRisk factorsCommon reasonPatientsDiscontinuationTherapy
2016
Timing of Last Preoperative Dose of Infliximab Does Not Increase Postoperative Complications in Inflammatory Bowel Disease Patients
Alsaleh A, Gaidos JK, Kang L, Kuemmerle JF. Timing of Last Preoperative Dose of Infliximab Does Not Increase Postoperative Complications in Inflammatory Bowel Disease Patients. Digestive Diseases And Sciences 2016, 61: 2602-2607. PMID: 27126205, PMCID: PMC4982818, DOI: 10.1007/s10620-016-4171-9.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal AbscessAdolescentAdultAnastomotic LeakChildColitis, UlcerativeCrohn DiseaseDigestive System Surgical ProceduresFemaleGastrointestinal AgentsHumansIleusInflammatory Bowel DiseasesInfliximabIntestinal ObstructionMaleMiddle AgedPostoperative ComplicationsPreoperative CareReoperationRetrospective StudiesRisk FactorsSurgical Wound InfectionTime FactorsVenous ThromboembolismYoung AdultConceptsLast preoperative dosePostoperative complicationsInflammatory bowel diseasePreoperative doseLast doseUlcerative colitisCrohn's diseaseInflammatory bowel disease patientsMethodsRetrospective chart reviewBowel disease patientsResultsNo significant associationIBD patientsPreoperative statusChart reviewPreoperative useBackgroundThe associationBowel diseaseSurgeon typeSurgery typeSteroid useDisease patientsInfliximabComplicationsPatientsDisease typeOvercoming challenges of treating inflammatory bowel disease in pregnancy
Gaidos JK, Kane SV. Overcoming challenges of treating inflammatory bowel disease in pregnancy. Expert Review Of Clinical Immunology 2016, 12: 871-878. PMID: 26981845, DOI: 10.1586/1744666x.2016.1166958.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseBowel diseasePeak reproductive yearsHealth care providersReproductive yearsCurrent treatmentCare providersPatient questionsBetter outcomesDate evidencePregnancyTherapeutic monitoringOverall managementExpert recommendationsDiseaseMultiple mechanismsPatientsProvidersReviewCare
2012
Prospective evaluation of the long-term outcomes after deep small-bowel spiral enteroscopy in patients with obscure GI bleeding
Williamson JB, Judah JR, Gaidos JK, Collins DP, Wagh MS, Chauhan SS, Zoeb S, Buscaglia JM, Yan H, Hou W, Draganov PV. Prospective evaluation of the long-term outcomes after deep small-bowel spiral enteroscopy in patients with obscure GI bleeding. Gastrointestinal Endoscopy 2012, 76: 771-778. PMID: 22771101, DOI: 10.1016/j.gie.2012.05.025.Peer-Reviewed Original ResearchConceptsObscure GI bleedingBlood transfusion requirementsGI bleedingLong-term followAdditional therapeutic proceduresTransfusion requirementsSpiral enteroscopyIron supplementationHemoglobin valuesTherapeutic proceduresLong-term clinical outcomesOvert GI bleedingProspective cohort studySingle-center studyAcademic referral centerLong-term outcomesMean hemoglobin valuesSerum hemoglobin valuesOvert bleedingAdverse eventsCohort studyReferral centerClinical outcomesProspective evaluationTherapeutic maneuvers
2011
Retrograde spiral enteroscopy: feasibility, success, and safety in a series of 22 patients
Nagula S, Gaidos J, Draganov PV, Bucobo JC, Cho B, Hernandez Y, Buscaglia JM. Retrograde spiral enteroscopy: feasibility, success, and safety in a series of 22 patients. Gastrointestinal Endoscopy 2011, 74: 699-702. PMID: 21762908, DOI: 10.1016/j.gie.2011.05.017.Peer-Reviewed Original Research
2010
Prospective Evaluation of Gastroenterologist-Guided, Nurse-Administered Standard Sedation for Spiral Deep Small Bowel Enteroscopy
Judah JR, Collins D, Gaidos JK, Hou W, Forsmark CE, Draganov PV. Prospective Evaluation of Gastroenterologist-Guided, Nurse-Administered Standard Sedation for Spiral Deep Small Bowel Enteroscopy. Digestive Diseases And Sciences 2010, 55: 2584-2591. PMID: 20632098, DOI: 10.1007/s10620-010-1335-x.Peer-Reviewed Original ResearchConceptsSmall bowel enteroscopyDeep small bowel enteroscopyDeep enteroscopyStandard sedationMethodsThis prospective case seriesLigament of TreitzProspective case seriesMean insertion depthTotal procedure timePresence of adhesionsSpiral overtubeMinor complicationsConsecutive patientsPatient characteristicsSedation groupCase seriesProspective evaluationFrequent findingEnteroscopyProcedure timeSedationPatientsPositive findingsAmerican SocietyAnesthesiologists
2008
A decision analysis study of the value of a liver biopsy in nonalcoholic steatohepatitis
Gaidos JK, Hillner BE, Sanyal AJ. A decision analysis study of the value of a liver biopsy in nonalcoholic steatohepatitis. Liver International 2008, 28: 650-658. PMID: 18331241, DOI: 10.1111/j.1478-3231.2008.01693.x.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseLiver biopsyLiver diseasePrevalence of NAFLDEarly liver biopsyPrevalent clinical syndromeTransplant-eligible patientsAdvanced liver diseaseInitial liver biopsyFatty liver diseaseSeverity of diseaseCryptogenic cirrhosisEligible patientsEarly biopsyLiver histologyDecision analysis studiesNonalcoholic steatohepatitisSurgical interventionClinical syndromeEarly treatmentStudy groupLB groupMortality rateBiopsy categoriesLower mortality