2020
Genetically Determined Omega-3 Polyunsaturated Fatty Acids and Lung Function: A Mendelian Randomization Analysis
Patchen B, Xu J, Hancock D, Cassano P. Genetically Determined Omega-3 Polyunsaturated Fatty Acids and Lung Function: A Mendelian Randomization Analysis. Current Developments In Nutrition 2020, 4: nzaa061_101. PMCID: PMC7259102, DOI: 10.1093/cdn/nzaa061_101.Peer-Reviewed Original ResearchAssociated with FEV1Multivariable MRMendelian randomizationForced vital capacityHeart and Aging ResearchInverse variance weighted methodHealth training programsMendelian randomization analysisVariance weighted methodGenome-wide association dataImprove causal inferenceCross-sectional studyLung functionNational InstituteWald ratioDigestive and Kidney DiseasesSample MRUnivariable MREpidemiology ConsortiumUK BiobankResidual confoundingNational Institute of DiabetesRandomization analysisTraining programForced expiratory volume
2018
Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function
Xu J, Bartz T, Chittoor G, Eiriksdottir G, Manichaikul A, Sun F, Terzikhan N, Zhou X, Booth S, Brusselle G, de Boer I, Fornage M, Frazier-Wood A, Graff M, Gudnason V, Harris T, Hofman A, Hou R, Houston D, Jacobs D, Kritchevsky S, Latourelle J, Lemaitre R, Lutsey P, O’Connor G, Oelsner E, Pankow J, Psaty B, Rohde R, Rich S, Rotter J, Smith L, Stricker B, Voruganti V, Wang T, Zillikens M, Barr R, Dupuis J, Gharib S, Lahousse L, London S, North K, Smith A, Steffen L, Hancock D, Cassano P. Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function. British Journal Of Nutrition 2018, 120: 1159-1170. PMID: 30205856, PMCID: PMC6263170, DOI: 10.1017/s0007114518002180.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAgingBlack or African AmericanBlack PeopleCross-Sectional StudiesFemaleForced Expiratory VolumeGenome, HumanHeartHeart DiseasesHumansLungLung DiseasesMaleMiddle AgedMolecular EpidemiologyProspective StudiesRegression AnalysisRespiratory Function TestsSmokingVital CapacityVitamin DWhite PeopleConceptsHeart and Aging ResearchForced vital capacityEuropean ancestryVitamin DNever smokersMeta-analysisAfrican ancestryHigher 25(OH)DPulmonary functionGenomic Epidemiology ConsortiumSerum 25-hydroxyvitamin DAssociation of serum vitamin DSerum vitamin DEpidemiology ConsortiumForced expiratory volumeEffect modificationFormer smokersSmoking statusSerum 25(OH)DVulnerable populationsAging researchSmokersEpidemiological studiesExpiratory volumeVital capacity
2017
Dietary Patterns and Lung Function: Assessment of the Alternative Health Eating Index‐2010 (AHEI‐2010) and Rate of Change in Forced Expiratory Volume in the First Second (FEV 1 )
Rettig S, Xu J, Karr A, Tang W, Guertin K, Goodman P, Minasian L, Lippman S, Klein E, Cassano P. Dietary Patterns and Lung Function: Assessment of the Alternative Health Eating Index‐2010 (AHEI‐2010) and Rate of Change in Forced Expiratory Volume in the First Second (FEV 1 ). The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.167.8.Peer-Reviewed Original ResearchAHEI-2010 scoreFood frequency questionnaireAHEI-2010US Dietary GuidelinesNever/former smokersDietary guidelinesRate of declineAlternative Healthy Eating Index-2010Dietary patternsMeasure of overall dietary qualitySmoking statusHealthy Eating Index-2010Assess usual dietary intakesDietary intakeOverall dietary qualityForced expiratory volumeFEV 1Lung functionUsual dietary intakeStudies of dietStatistically significant interactionExpiratory volumeDietary qualityFrequency questionnaireLinear mixed-effects models