2008
Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates
Wisnewski AV, Liu Q, Liu J, Redlich CA. Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates. Clinical & Experimental Allergy 2008, 38: 957-967. PMID: 18498542, PMCID: PMC3131007, DOI: 10.1111/j.1365-2222.2008.02982.x.Peer-Reviewed Original ResearchMeSH KeywordsAdipokinesAdministration, InhalationAlbuminsAntigens, CDBlotting, WesternCells, CulturedChemokine CCL2Chitinase-3-Like Protein 1ChitinasesCyanatesEnzyme-Linked Immunosorbent AssayGene ExpressionGlycoproteinsHumansImmunity, InnateIntramolecular OxidoreductasesIsocyanatesLectinsLeukocytes, MononuclearLysosomesMacrophage Migration-Inhibitory FactorsMicroscopy, FluorescenceOligonucleotide Array Sequence AnalysisPolymerase Chain ReactionPolymorphism, GeneticProteinsRNAConceptsPeripheral blood mononuclear cellsInnate immune responseImmune responsePercentage of PBMCHuman peripheral blood mononuclear cellsFlow cytometrySystemic innate immune responseExposure-dependent decreaseMonocyte/macrophage traffickingHuman innate immune responseProtein expressionSpecific inhalation challengeBlood mononuclear cellsAdaptive immune responsesLow-density lipoproteinPattern recognition receptorsInhalation challengeOccupational asthmaClinical spectrumControl antigenMononuclear cellsHDI exposureSerum concentrationsAdaptive immunityGene/protein expression
2004
High-throughput microarray detection of olfactory receptor gene expression in the mouse
Zhang X, Rogers M, Tian H, Zhang X, Zou DJ, Liu J, Ma M, Shepherd GM, Firestein SJ. High-throughput microarray detection of olfactory receptor gene expression in the mouse. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 14168-14173. PMID: 15377787, PMCID: PMC521132, DOI: 10.1073/pnas.0405350101.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnimalsChromosomesCluster AnalysisGene Expression ProfilingGenomeLungMaleMiceMice, Inbred StrainsOlfactory MucosaOligonucleotide Array Sequence AnalysisReceptors, OdorantTestisVomeronasal OrganConceptsOlfactory receptorsExpression patternsGene expressionOlfactory receptor gene expressionReceptor geneVomeronasal receptor genesOlfactory receptor genesHigh-density oligonucleotide arraysMouse olfactory receptorGenomic locationHigh-throughput methodGenomic sequencesOlfactory sensory epitheliumSpecific expressionGenesOligonucleotide arraysSpatial expressionCustom arrayLarge familyReceptor gene expressionSensory epitheliumThroughput methodMicroarray detectionExpressionLarge number