2023
Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2020
Red Blood Cell Transfusions and Outcomes After Intracerebral Hemorrhage
Roh DJ, Carvalho Poyraz F, Magid-Bernstein J, Elkind MSV, Agarwal S, Park S, Claassen J, Connolly ES, Hod E, Murthy SB. Red Blood Cell Transfusions and Outcomes After Intracerebral Hemorrhage. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 105317. PMID: 32992186, PMCID: PMC7686150, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105317.Peer-Reviewed Original ResearchConceptsRBC transfusionICH outcomeDisease severityComorbidity burdenICH hospitalizationsPoor outcomeRed blood cell transfusionICD-9-CM codesBlood cell transfusionAdditional prospective studiesRed blood cell levelsIntracerebral hemorrhage outcomesNationwide Inpatient SampleLower red blood cell levelsBlood cell levelsBaseline comorbiditiesHospital mortalityTransfusion exposureVentriculostomy drainsCell transfusionLow comorbidityIntracerebral hemorrhageMechanical ventilationProspective studyInpatient SampleA rare case of HIV CNS escape in a patient previously considered a viral controller
Magid-Bernstein J, Guo CY, Chow FC, Thakur KT. A rare case of HIV CNS escape in a patient previously considered a viral controller. International Journal Of STD & AIDS 2020, 31: 694-698. PMID: 32538333, DOI: 10.1177/0956462420922452.Peer-Reviewed Original ResearchConceptsViral controllersViral suppressionFungal CNS infectionsNon-HIV infectionsPerinatal HIV infectionHuman immunodeficiency virus ribonucleic acid levelsCentral nervous systemRibonucleic acid levelsCNS infectionsHIV RNAHIV infectionRare caseCerebrospinal fluidNervous systemAcid levelsInfectionYoung menIndependent replicationHIVPatientsSuppressionSetting
2017
Human CD39+ Treg Cells Express Th17-Associated Surface Markers and Suppress IL-17 via a Stat3-Dependent Mechanism
Magid-Bernstein JR, Rohowsky-Kochan CM. Human CD39+ Treg Cells Express Th17-Associated Surface Markers and Suppress IL-17 via a Stat3-Dependent Mechanism. Journal Of Interferon & Cytokine Research 2017, 37: 153-164. PMID: 28387597, PMCID: PMC6435349, DOI: 10.1089/jir.2016.0071.Peer-Reviewed Original ResearchConceptsIL-17STAT3-dependent mechanismIL-23RHuman CD4T effector cellsIFN-γ productionEctonucleotidase CD39Autologous CD4Regulatory cellsAutoimmune responseEffector cellsAutoimmune diseasesTranscription factor STAT3Immune responseProliferative responseCD25CD4CD39Human CD39Surface markersSTAT3 activationCCR6STAT3CellsFirst evidence
2016
Unexpected Rapid Improvement and Neurogenic Stunned Myocardium in a Patient With Acute Motor Axonal Neuropathy
Magid-Bernstein J, Al-Mufti F, Merkler AE, Roh D, Patel S, May TL, Agarwal S, Claassen J, Park S. Unexpected Rapid Improvement and Neurogenic Stunned Myocardium in a Patient With Acute Motor Axonal Neuropathy. Journal Of Clinical Neuromuscular Disease 2016, 17: 135-141. PMID: 26905914, DOI: 10.1097/cnd.0000000000000109.Peer-Reviewed Original ResearchConceptsNeurogenic stunned myocardiumMotor axonal neuropathyStunned myocardiumAxonal neuropathyAcute motor axonal neuropathyUpper respiratory illnessBarré syndromeNeurologic symptomsAntiganglioside antibodiesComplete tetraplegiaHealthy womenRespiratory illnessLumbar punctureMotor functionPhysical therapyRare casePlasmapheresisMycoplasma pneumoniaeRapid improvementAreflexiaNeuropathyPatientsTetraplegiaMyocardiumBlood