2024
Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model
Bottom-Tanzer S, Corella S, Meyer J, Sommer M, Bolaños L, Murphy T, Quiñones S, Heiney S, Shtrahman M, Whalen M, Oren R, Higley M, Cardin J, Noubary F, Armbruster M, Dulla C. Traumatic brain injury disrupts state-dependent functional cortical connectivity in a mouse model. Cerebral Cortex 2024, 34: bhae038. PMID: 38365273, PMCID: PMC11486687, DOI: 10.1093/cercor/bhae038.Peer-Reviewed Original ResearchConceptsControlled cortical impactTraumatic brain injuryFunctional connectivityDisrupted functional connectivityAssociated with improved cognitionReduced theta powerBrain injuryHuman TBI patientsModel of traumatic brain injuryBehavioral state-dependent changesNetwork connectivity changesFunctional cortical connectivityBrain regionsTheta powerConnectivity changesState-dependent changesCortical impactPeriods of locomotionCortical connectivityTBI patientsRodent modelsECoG activityMotor dysfunctionCortexInjured cortex
2011
Dissecting local circuits in vivo: Integrated optogenetic and electrophysiology approaches for exploring inhibitory regulation of cortical activity
Cardin JA. Dissecting local circuits in vivo: Integrated optogenetic and electrophysiology approaches for exploring inhibitory regulation of cortical activity. Journal Of Physiology-Paris 2011, 106: 104-111. PMID: 21958624, PMCID: PMC3277809, DOI: 10.1016/j.jphysparis.2011.09.005.Peer-Reviewed Original Research
1999
Memory suppressor genes: Enhancing the relationship between synaptic plasticity and memory storage
Cardin J, Abel T. Memory suppressor genes: Enhancing the relationship between synaptic plasticity and memory storage. Journal Of Neuroscience Research 1999, 58: 10-23. PMID: 10491568, DOI: 10.1002/(sici)1097-4547(19991001)58:1<10::aid-jnr3>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsMemory suppressor genesSuppressor gene productGene productsSuppressor geneTranscriptional regulatory proteinsCell-cell interactionsIntracellular signaling cascadesSynaptic plasticityTranscriptional controlRegulatory proteinsSignaling cascadesKinase activityHuman disordersGenesInhibitory constraintCell surfaceFuture pharmaceuticalsLong-term potentiationProteinPotential targetMammalian hippocampusPlasticityLong-term facilitationRecent evidenceDrosophila