2022
Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity
Lohani S, Moberly A, Benisty H, Landa B, Jing M, Li Y, Higley M, Cardin J. Spatiotemporally heterogeneous coordination of cholinergic and neocortical activity. Nature Neuroscience 2022, 25: 1706-1713. PMID: 36443609, PMCID: PMC10661869, DOI: 10.1038/s41593-022-01202-6.Peer-Reviewed Original ResearchConceptsCortical network activityBehavioral statesCholinergic modulationAnimal's behavioral stateCholinergic signalingAwake miceCortical functionFunctional reorganizationNeuromodulatory influencesDifferent motor behaviorsNeocortical activityAcetylcholineMotor behaviorCortical networksRecent evidenceBrain activityFunctional segregationNeocortexMesoscopic imagingHeterogeneous signalsNetwork activityBehavioral markersBehavioral variablesCircuit dynamicsCholinergic
1999
Memory suppressor genes: Enhancing the relationship between synaptic plasticity and memory storage
Cardin J, Abel T. Memory suppressor genes: Enhancing the relationship between synaptic plasticity and memory storage. Journal Of Neuroscience Research 1999, 58: 10-23. PMID: 10491568, DOI: 10.1002/(sici)1097-4547(19991001)58:1<10::aid-jnr3>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsMemory suppressor genesSuppressor gene productGene productsSuppressor geneTranscriptional regulatory proteinsCell-cell interactionsIntracellular signaling cascadesSynaptic plasticityTranscriptional controlRegulatory proteinsSignaling cascadesKinase activityHuman disordersGenesInhibitory constraintCell surfaceFuture pharmaceuticalsLong-term potentiationProteinPotential targetMammalian hippocampusPlasticityLong-term facilitationRecent evidenceDrosophila