Featured Publications
COVID-19 Vaccination–Associated Myocarditis in Adolescents
Jain SS, Steele JM, Fonseca B, Huang S, Shah S, Maskatia SA, Buddhe S, Misra N, Ramachandran P, Gaur L, Eshtehardi P, Anwar S, Kaushik N, Han F, Chaudhuri NR, Grosse-Wortmann L. COVID-19 Vaccination–Associated Myocarditis in Adolescents. Pediatrics 2021, 148: e2021053427. PMID: 34389692, DOI: 10.1542/peds.2021-053427.Peer-Reviewed Original ResearchConceptsCardiovascular magnetic resonanceMultisystem inflammatory syndromeMyocardial tissue changesInflammatory syndromeVentricular dysfunctionMyocardial injuryTissue changesExcellent short-term outcomesMild left ventricular dysfunctionDifferent pediatric age groupsQuick clinical recoveryLeft ventricular dysfunctionResolution of symptomsRetrospective multicenter studyPediatric age groupShort-term outcomesShort-term prognosisMessenger RNA vaccinesLate gadolinium enhancementYears of ageLake Louise criteriaSignificant dysrhythmiasHospital courseClinical characteristicsClinical recovery
2023
Longitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination
NV B, McCollum S, Faherty E, Steele J, Karnik R. Longitudinal Assessment of Left Ventricular Function in Patients with Myopericarditis After mRNA COVID-19 Vaccination. Pediatric Cardiology 2023, 45: 1524-1532. PMID: 37294336, PMCID: PMC10251331, DOI: 10.1007/s00246-023-03200-2.Peer-Reviewed Original ResearchLeft ventricular longitudinal strainMRNA COVID-19 vaccinationCOVID-19 vaccinationSubclinical myocardial injuryEjection fractionFractional shorteningInitial presentationMyocardial injurySingle-center reviewMedian ejection fractionLeft ventricular functionVentricular longitudinal strainTime 0Area-length methodWilcoxon signed-rank testAcute illnessDiastolic functionVentricular functionDiastolic parametersLV functionRisk stratificationMyocardial recoveryTissue DopplerSigned-rank testMyopericarditis
2021
Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C
Shah HP, Frye R, Chang S, Faherty E, Steele J, Karnik R. Challenges of Diagnosing Viral Myocarditis in Adolescents in the Era of COVID‐19 and MIS‐C. Case Reports In Pediatrics 2021, 2021: 4797498. PMID: 34616578, PMCID: PMC8490073, DOI: 10.1155/2021/4797498.Peer-Reviewed Case Reports and Technical NotesPediatric myocarditisElevated inflammatory markersMultisystem inflammatory syndromeShortness of breathDiagnosis of myocarditisSudden cardiac deathCOVID-19Electrocardiogram findingsInflammatory markersInflammatory syndromeChest tightnessCardiac deathMale presentingAnnual incidenceClinical presentationD-dimerViral myocarditisMyocardial injuryClinical conundrumSubclinical presentationMyocarditisRare diseaseClinical experienceTrue prevalenceCurrent Covid-19 pandemic era