2021
Evolution of the liver biopsy and its future
Jain D, Torres R, Celli R, Koelmel J, Charkoftaki G, Vasiliou V. Evolution of the liver biopsy and its future. Translational Gastroenterology And Hepatology 2021, 6: 20-20. PMID: 33824924, PMCID: PMC7829074, DOI: 10.21037/tgh.2020.04.01.Peer-Reviewed Original ResearchLiver biopsyLiver tissueClinical practicePost-transplant complicationsRoutine clinical practiceTissue content analysisCommon indicationLiver diseaseNon-invasive methodMultiphoton microscopyHistologic evaluationMedical disordersEffective treatmentNew therapiesBiopsyClinical diagnosisClinical researchTissue samplesVisualization of tissuesTissue sectionsPrognostic capabilityClinical workflowImproved clinical diagnosisTissueDiagnosis
2019
Software tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values
Koelmel J, Cochran J, Ulmer C, Levy A, Patterson R, Olsen B, Yost R, Bowden J, Garrett T. Software tool for internal standard based normalization of lipids, and effect of data-processing strategies on resulting values. BMC Bioinformatics 2019, 20: 217. PMID: 31035918, PMCID: PMC6489209, DOI: 10.1186/s12859-019-2803-8.Peer-Reviewed Original ResearchConceptsInternal standardClose retention timesLC-MS/MS studiesMultiple internal standardsTarget analytesLipidomics workflowsLipid standardsMS studiesNormalization of lipidsPeak areaAdductsLipid structureFeature findingAnalytesHuman plasmaBiological systemsLipid classesIndividual internal standardsEther-linked phosphatidylcholinesClinical utilityRetention timeClinical diagnosisQuantitation processLipid speciesUnderstanding of health