2020
Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features
Pathak R, Goldberg SB, Canavan M, Herrin J, Hoag JR, Salazar MC, Papageorge M, Ermer T, Boffa DJ. Association of Survival With Adjuvant Chemotherapy Among Patients With Early-Stage Non–Small Cell Lung Cancer With vs Without High-Risk Clinicopathologic Features. JAMA Oncology 2020, 6: 1741-1750. PMID: 32940636, PMCID: PMC7499246, DOI: 10.1001/jamaoncol.2020.4232.Peer-Reviewed Original ResearchConceptsNode-negative non-small cell lung cancerHigh-risk pathologic featuresNon-small cell lung cancerAdjuvant chemotherapyCell lung cancerPathologic featuresTumor sizeSurvival benefitCohort studyLung cancerNode-negative NSCLCEarly-stage non-small cell lung cancerCox proportional hazards regression modelHigh-risk clinicopathologic featuresProportional hazards regression modelsNational Cancer DatabaseRetrospective cohort studyTreatment-naive patientsAdjuvant chemotherapy useHigh-risk featuresAssociation of survivalHazards regression modelsImmortal time biasChemotherapy useEligible patients
2017
Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer
Ruddy KJ, Van Houten HK, Sangaralingham LR, Freedman RA, Thompson CA, Hashmi SK, Jemal A, Haddad TC, Mougalian S, Herrin J, Gross C, Shah N. Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer. Breast Cancer Research And Treatment 2017, 164: 515-525. PMID: 28493045, DOI: 10.1007/s10549-017-4280-y.Peer-Reviewed Original ResearchConceptsAcute care useEarly-stage breast cancerCare useBreast cancerAdjuvant chemotherapyContemporary adjuvant chemotherapyAcute care needsCommercial insurance databaseEmergency department visitsED visit ratesRate of hospitalizationOncology Care ModelChemotherapy initiationChemotherapy regimenEligible patientsED visitsDepartment visitsTreatment regimenAcute careInsurance databaseAdministration periodAdjusted ratesCare modelCare needsVisit rates