2022
Is it the time to integrate novel sequencing technologies into clinical practice?
VanOudenhove J, Halene S, Mendez L. Is it the time to integrate novel sequencing technologies into clinical practice? Current Opinion In Hematology 2022, 30: 70-77. PMID: 36602939, DOI: 10.1097/moh.0000000000000754.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNovel sequencing technologiesSequencing technologiesUnprecedented biological insightsNext-generation sequencing techniquesDNA sequencing technologiesHigh-throughput NGSRare cell populationsBiological insightsMultiomics approachSequencing techniquesGenotype-phenotype correlationClonal diversityCellular resolutionMechanistic insightsCell populationsPhenotype correlationMyeloid diseasesClonesClonal hierarchyClonal haematopoiesisResidual clonesInsightsSeqDiversityImproved capture
2017
Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle
VanOudenhove J, Grandy R, Ghule P, Lian J, Stein J, Zaidi S, Stein G. Unique Regulatory Mechanisms for the Human Embryonic Stem Cell Cycle. Journal Of Cellular Physiology 2017, 232: 1254-1257. PMID: 27532275, PMCID: PMC5315681, DOI: 10.1002/jcp.25567.Peer-Reviewed Original ResearchConceptsCell cyclePluripotent human embryonic stem cellsPluripotent cell cyclePluripotent cell populationHuman embryonic stem cellsEmbryonic stem cellsG1 periodCell cycle pauseMesodermal lineage cellsEpigenetic mechanismsEctodermal differentiationRegulatory eventsUnrestricted proliferationLineage cellsStem cellsCell populationsUnique mechanismRecent findingsDifferentiationPluripotencyCellsMechanismProliferationCycle