2019
Prenatal nicotine sex-dependently alters adolescent dopamine system development
Dwyer JB, Cardenas A, Franke RM, Chen Y, Bai Y, Belluzzi JD, Lotfipour S, Leslie FM. Prenatal nicotine sex-dependently alters adolescent dopamine system development. Translational Psychiatry 2019, 9: 304. PMID: 31740669, PMCID: PMC6861272, DOI: 10.1038/s41398-019-0640-1.Peer-Reviewed Original ResearchConceptsDopamine systemStriatal dopamine transporter bindingNorepinephrine transporterCocaine-induced locomotor activityGestational day 4Role of D2Postnatal day 32Dopamine transporter bindingCatechol-O-methyl transferaseElectronic nicotine delivery systemsCocaine-induced behaviorsPublic health initiativesSex-independent effectsNicotine delivery systemsG protein couplingNaïve damsMaternal smokingNicotine patchClinical deficitsDopamine turnoverOsmotic minipumpsPlasma levelsNeurobehavioral deficitsPregnant damsReceptor expression
2018
A Developmental Perspective of Dopaminergic Dysfunction in Tourette Syndrome
Dwyer JB. A Developmental Perspective of Dopaminergic Dysfunction in Tourette Syndrome. Biological Psychiatry 2018, 84: e33-e35. PMID: 30115244, DOI: 10.1016/j.biopsych.2018.07.008.Peer-Reviewed Original Research