2018
Effect of epileptiform abnormality burden on neurologic outcome and antiepileptic drug management after subarachnoid hemorrhage
Zafar SF, Postma EN, Biswal S, Boyle EJ, Bechek S, O'Connor K, Shenoy A, Kim J, Shafi MS, Patel AB, Rosenthal ES, Westover MB. Effect of epileptiform abnormality burden on neurologic outcome and antiepileptic drug management after subarachnoid hemorrhage. Clinical Neurophysiology 2018, 129: 2219-2227. PMID: 30212805, PMCID: PMC6478499, DOI: 10.1016/j.clinph.2018.08.015.Peer-Reviewed Original ResearchConceptsAnti-epileptic drugsAneurysmal subarachnoid hemorrhageEpileptiform abnormalitiesWorse outcomesSubarachnoid hemorrhageHigh-grade aSAH patientsEvidence-based treatment protocolsGlasgow Outcome ScoreAntiepileptic drug managementStandard prophylaxisNeurologic outcomeProphylactic protocolASAH patientsOutcome scoresDrug managementHigh burdenRetrospective analysisTreatment protocolOutcome measuresPatientsDaily burdenRhythmic activityFirst dayOutcomesBurden
2017
Electronic Health Data Predict Outcomes After Aneurysmal Subarachnoid Hemorrhage
Zafar SF, Postma EN, Biswal S, Fleuren L, Boyle EJ, Bechek S, O’Connor K, Shenoy A, Jonnalagadda D, Kim J, Shafi MS, Patel AB, Rosenthal ES, Westover MB. Electronic Health Data Predict Outcomes After Aneurysmal Subarachnoid Hemorrhage. Neurocritical Care 2017, 28: 184-193. PMID: 28983801, PMCID: PMC5886829, DOI: 10.1007/s12028-017-0466-8.Peer-Reviewed Original ResearchConceptsAneurysmal subarachnoid hemorrhageGlasgow Outcome ScaleWhite blood cellsIntracranial pressureAPACHE IIElectronic health dataSubarachnoid hemorrhageBetter outcomesSingle-center retrospective cohort studyDischarge Glasgow Outcome ScaleEarly goal-directed therapyAPACHE II scoreGoal-directed therapyRetrospective cohort studyMean arterial pressureRisk stratification scoresAdmission APACHE IIPredictors of outcomeMultivariate analysis predictorsLogistic regression modelsHealth dataAdmission dayII scoreNeurologic outcomeArterial pressure