2017
Epileptiform abnormalities predict delayed cerebral ischemia in subarachnoid hemorrhage
Kim JA, Rosenthal ES, Biswal S, Zafar S, Shenoy AV, O'Connor KL, Bechek SC, Moura J, Shafi MM, Patel AB, Cash SS, Westover MB. Epileptiform abnormalities predict delayed cerebral ischemia in subarachnoid hemorrhage. Clinical Neurophysiology 2017, 128: 1091-1099. PMID: 28258936, PMCID: PMC5476529, DOI: 10.1016/j.clinph.2017.01.016.Peer-Reviewed Original ResearchConceptsCerebral ischemiaSubarachnoid hemorrhageRisk of DCISecondary cerebral injuryRhythmic delta activityAbnormal neural activityNew potential targetsCerebral injuryEarly patientsEpileptiform abnormalitiesMedical recordsEpileptiform dischargesRetrospective analysisHigh riskDCI developmentDelta activityPatientsNovel markerIschemiaSurvival analysis methodsCumulative probabilityPotential targetNeural activityNew markersDCI
2009
Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue
Zhang J, Laiwalla F, Kim JA, Urabe H, Van Wagenen R, Song YK, Connors BW, Zhang F, Deisseroth K, Nurmikko AV. Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue. Journal Of Neural Engineering 2009, 6: 055007. PMID: 19721185, PMCID: PMC2921864, DOI: 10.1088/1741-2560/6/5/055007.Peer-Reviewed Original ResearchConceptsMillisecond temporal controlIntegrated deviceNeural activityOptical stimulationHybrid deviceArray deviceProspective clinical treatmentMouse brain slicesOptical waveguidesOptical deliveryGanglion cellsBrain slicesNeurological diseasesRecording capabilitiesMouse retinaBrain tissueClinical treatmentElectrophysiological meansStimulation siteRecording arrayLocal deliveryDevicesRetinal photoreceptorsNeuronal spiking activityStimulation