Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency
Elizondo G, Saini A, Gonzalez de Alba C, Gregor A, Harding C, Gillingham M, Vinocur J. Cardiac phenotype in adolescents and young adults with long-chain 3-hydroxyacyl CoA dehydrogenase (LCHAD) deficiency. Genetics In Medicine 2024, 26: 101123. PMID: 38501492, DOI: 10.1016/j.gim.2024.101123.Peer-Reviewed Original ResearchLong-chain 3-hydroxyacyl-CoA dehydrogenase deficiencyLong-chain 3-hydroxyacyl-CoA dehydrogenaseCardiac involvementCardiac arrestMetabolic decompensationCardiac phenotypeDilated cardiomyopathyLong-chain 3-hydroxyacyl-CoA dehydrogenase deficient patientsEpisodes of metabolic decompensationEnd-stage dilated cardiomyopathyOut-of-hospital cardiac arrestAcute cardiac decompensationIn-hospital cardiac arrestFatty acid oxidation disordersLife-threatening arrhythmiasInfantile dilated cardiomyopathySudden cardiac arrestPotential risk factorsCardiac manifestationsCardiac decompensationRestrictive cardiomyopathyRecurrent episodesRetrospective cohortRisk stratificationPeripheral neuropathy