2016
PhyloOncology: Understanding cancer through phylogenetic analysis
Somarelli JA, Ware KE, Kostadinov R, Robinson JM, Amri H, Abu-Asab M, Fourie N, Diogo R, Swofford D, Townsend JP. PhyloOncology: Understanding cancer through phylogenetic analysis. Biochimica Et Biophysica Acta (BBA) - Reviews On Cancer 2016, 1867: 101-108. PMID: 27810337, PMCID: PMC9583457, DOI: 10.1016/j.bbcan.2016.10.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdaptation, PhysiologicalAlgorithmsAnimalsBiomarkers, TumorCell Transformation, NeoplasticEvolution, MolecularGene Expression Regulation, NeoplasticGenetic FitnessGenetic Predisposition to DiseaseGenomicsHeredityHumansModels, GeneticMutationNeoplasmsPedigreePhenotypePhylogenySignal TransductionSystems BiologyTime FactorsConceptsDr. Robert A. GatenbyGenome-scale dataSystems biology approachPowerful systems biology approachUse of phylogeneticsPhylogenetic analysisBiology approachPhylogenetic applicationsSubclonal evolutionCancer biologyCancer progressionSuite of algorithmsPhylogeneticsCancer data setsCancer samplesImproved therapeutic interventionRobust approachDecades of researchFundamental insightsNew toolBiologyDiverse fieldsGatenbyData setsTherapeutic interventions
2007
Profiling Phylogenetic Informativeness
Townsend JP. Profiling Phylogenetic Informativeness. Systematic Biology 2007, 56: 222-231. PMID: 17464879, DOI: 10.1080/10635150701311362.Peer-Reviewed Original ResearchConceptsPhylogenetic informativenessRapid radiationPhylogenetic studiesCharacter samplingBroad phylogenetic studyRapid adaptive radiationGenome-scale dataAddition of charactersAdaptive radiationPhylogenetic signalSoft polytomiesPhylogenetic profilesPhylogenetic hypothesisAncestral lineagePhylogenetic experimentsEarly metazoansPhylogenetic charactersSequence dataMuroid rodentsHistorical radiationPolytomyBase pairsGenesC-MycGenes BRCA1