2013
Sciatic nerve regeneration is not inhibited by anti-NGF antibody treatment in the adult rat
Lankford K, Arroyo E, Liu C, Somps C, Zorbas M, Shelton D, Evans M, Hurst S, Kocsis J. Sciatic nerve regeneration is not inhibited by anti-NGF antibody treatment in the adult rat. Neuroscience 2013, 241: 157-169. PMID: 23531437, DOI: 10.1016/j.neuroscience.2013.03.024.Peer-Reviewed Original ResearchConceptsNerve growth factorAdult ratsNerve regenerationFunctional recoveryAnti-NGF antibody treatmentElevated nerve growth factorUnilateral sciatic nerve crushDorsal root ganglion neuronsAnti-NGF antibodySciatic nerve crushType of painVehicle-treated animalsSciatic nerve regenerationPost nerve injuryNovel therapeutic approachesCell body sizePeripheral nerve regenerationFluro-GoldPeripheral nervous system developmentNerve injuryPain modelNerve crushPain managementAntibody treatmentGait recovery
1993
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve
Lim J, Utzschneider D, Sakatani K, Kocsis J. The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve. Brain Research 1993, 72: 15-20. PMID: 8384095, DOI: 10.1016/0165-3806(93)90155-4.Peer-Reviewed Original ResearchConceptsOptic nerveRat optic nerveEffect of GABAMD ratsNipecotic acidGABA sensitivityGABA uptake inhibitor nipecotic acidNormal optic nervesGABAA receptor agonistOptic nerve axonsEarly postnatal periodCentral nervous system axonsThird postnatal weekSucrose gap techniqueResult of myelinationLarger GABAAxonal excitabilityControl ratsGABAA receptorsEndogenous releasePostnatal periodPostnatal weekNerve sensitivityNerveGABA
1985
Differences between mammalian ventral and dorsal spinal roots in response to blockade of potassium channels during maturation
Bowe C, Kocsis J, Waxman S. Differences between mammalian ventral and dorsal spinal roots in response to blockade of potassium channels during maturation. Proceedings Of The Royal Society B 1985, 224: 355-366. PMID: 2410932, DOI: 10.1098/rspb.1985.0037.Peer-Reviewed Original ResearchConceptsDorsal spinal rootsSensory fibersMammalian motorPotassium channelsSpinal rootsAction potentialsRoot fibersCompound action potentialSingle sensory fibresDorsal root fibersVentral root fibersClasses of axonsIndividual action potentialsPharmacological blockadeVentral rootsYoung rootsSensory axonsWhole nervePotassium conductanceAxon responsesCourse of maturationBlockadeAxonsRoots resultsDifferential sensitivity