2013
Sural nerve defects after nerve biopsy or nerve transfer as a sensory regeneration model for peripheral nerve conduit implantation
Radtke C, Kocsis J, Reimers K, Allmeling C, Vogt P. Sural nerve defects after nerve biopsy or nerve transfer as a sensory regeneration model for peripheral nerve conduit implantation. Medical Hypotheses 2013, 81: 500-502. PMID: 23867139, DOI: 10.1016/j.mehy.2013.06.020.Peer-Reviewed Original ResearchConceptsConduit implantationNerve repairNerve biopsyNerve injurySural nerveAxonal regenerationNerve defectsAcute peripheral nerve injuryHuman nerve injurySural nerve graftRecovery of sensationPeripheral nerve injuryVon Frey filamentsExtent of injuryNerve graft harvestingCold allodyniaMajor morbidityNerve transferNerve stumpNerve graftsNeuroma formationNerve lengthDigital nerveGraft harvestingAutograft treatment
2001
Transplantation of Cryopreserved Adult Human Schwann Cells Enhances Axonal Conduction in Demyelinated Spinal Cord
Kohama I, Lankford K, Preiningerova J, White F, Vollmer T, Kocsis J. Transplantation of Cryopreserved Adult Human Schwann Cells Enhances Axonal Conduction in Demyelinated Spinal Cord. Journal Of Neuroscience 2001, 21: 944-950. PMID: 11157080, PMCID: PMC2605383, DOI: 10.1523/jneurosci.21-03-00944.2001.Peer-Reviewed Original ResearchConceptsHuman Schwann cellsSchwann cellsDorsal columnsSural nerveAxonal conductionIntra-axonal recording techniquesDorsal column lesionLegs of patientsDemyelinated spinal cordHuman sural nerveAdult human Schwann cellsFunctional remyelinationExtensive remyelinationCell-based therapiesMultiple sclerosisVascular diseaseSpinal cordWistar ratsConduction blockAdult CNSConduction velocityLesion zoneAction potentialsMonoclonal antibodiesLesions
1998
The delayed depolarization in rat cutaneous afferent axons is reduced following nerve transection and ligation, but not crush: Implications for injury‐induced axonal NA + channel reorganization
Sakai J, Honmou O, Kocsis J, Hashi K. The delayed depolarization in rat cutaneous afferent axons is reduced following nerve transection and ligation, but not crush: Implications for injury‐induced axonal NA + channel reorganization. Muscle & Nerve 1998, 21: 1040-1047. PMID: 9655122, DOI: 10.1002/(sici)1097-4598(199808)21:8<1040::aid-mus8>3.0.co;2-8.Peer-Reviewed Original ResearchConceptsCutaneous afferent axonsNerve injurySural nerveNerve transectionAfferent axonsAction potentialsCell bodiesCutaneous afferent neuronsPeripheral nerve injuryAfferent cell bodiesSucrose gap chamberRat sural nerveTarget disconnectionAfferent neuronsPeripheral targetsAxonal NaNerveRefractory periodAxonsTransectionCompound actionDepolarizationSimilar changesInjuryTarget connections