2001
[The role of transplanted astrocytes for the regeneration of CNS axons].
Imaizumi T, Lankford K, Kocsis J, Hashi K. [The role of transplanted astrocytes for the regeneration of CNS axons]. Brain And Nerve 脳と神経 2001, 53: 632-8. PMID: 11517487.Peer-Reviewed Original ResearchConceptsCompound action potentialRegenerated axonsSC transplantationAxonal regenerationAdult ratsLong-tract axonsMyelin associated proteinsDorsal column axonsRegeneration of axonsDC axonsCell transplantationDorsal rootsNeonatal ratsSpinal cordReduction of scarsHistological examinationTransplantationMammalian CNSCNS axonsAction potentialsAxonsMyelin formationLesionsThree daysRats
2000
Xenotransplantation of transgenic pig olfactory ensheathing cells promotes axonal regeneration in rat spinal cord
Imaizumi T, Lankford K, Burton W, Fodor W, Kocsis J. Xenotransplantation of transgenic pig olfactory ensheathing cells promotes axonal regeneration in rat spinal cord. Nature Biotechnology 2000, 18: 949-953. PMID: 10973214, PMCID: PMC2605371, DOI: 10.1038/79432.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedAxonsCD59 AntigensCell SeparationElectrophysiologyFlow CytometryFluorescent Antibody Technique, IndirectHumansImmunosuppression TherapyModels, BiologicalOlfactory NerveRatsRats, WistarRegenerationSchwann CellsSciatic NerveSpinal CordSwineTransgenesTransplantation, HeterologousConceptsAxonal regenerationSpinal cordSchwann cellsImpulse conductionLesion-control ratsDorsal column lesionTransplantation of olfactoryRat spinal cordConduction velocity measurementsComplement inhibitory proteinsHyperacute responseRegenerated axonsImmunosuppressed ratsTransection siteLesion sitePeripheral patternHost tractCordNormal axonsDonor cellsAxonsInhibitory proteinRatsDonor cell typeTransgenic pigsTransplantation of olfactory ensheathing cells or Schwann cells restores rapid and secure conduction across the transected spinal cord
Imaizumi T, Lankford K, Kocsis J. Transplantation of olfactory ensheathing cells or Schwann cells restores rapid and secure conduction across the transected spinal cord. Brain Research 2000, 854: 70-78. PMID: 10784108, DOI: 10.1016/s0006-8993(99)02285-4.Peer-Reviewed Original ResearchConceptsRegenerated axonsCell transplantationSpinal cordSchwann cellsTransection siteIsolated spinal cord preparationSpinal cord preparationTransplantation of olfactoryRat spinal cordSpinal cord axonsConduction velocity measurementsTransplantation of cellsCord preparationDorsal columnsAxonal regenerationAxon areaTransplantationImpulse conductionHost tractElectrophysiological recordingsAxonsNormal axonsDonor cellsNeuronal sourcesCord
1991
Tea‐sensitive potassium channels and inward rectification in regenerated rat sciatic nerve
Gardon T, Kocsis J, Waxman S. Tea‐sensitive potassium channels and inward rectification in regenerated rat sciatic nerve. Muscle & Nerve 1991, 14: 640-646. PMID: 1922170, DOI: 10.1002/mus.880140707.Peer-Reviewed Original ResearchConceptsCompound action potentialRat sciatic nerveNerve crushRegenerated axonsSciatic nerveRegenerated nervesInward rectificationIntra-axonal recording techniquesAdult rat sciatic nerveTEA-sensitive potassium channelsPotassium channelsRegenerated rat sciatic nerveSucrose gap recordingsSciatic nerve crushPeripheral nerve axonsWhole nerve recordingsIntra-axonal recordingsVoltage-sensitive sodium channelsCrush injuryNormal nervesSensitive relaxationRepetitive stimulationAfterhyperpolarizationGap recordingsNerve recordings
1987
Nodal spacing along regenerated axons following a crush lesion of the developing rat sciatic nerve
Hildebrand C, Mustafa G, Bowe C, Kocsis J. Nodal spacing along regenerated axons following a crush lesion of the developing rat sciatic nerve. Brain Research 1987, 32: 147-154. DOI: 10.1016/0165-3806(87)90148-9.Peer-Reviewed Original ResearchNodal spacing along regenerated axons following a crush lesion of the developing rat sciatic nerve.
Hildebrand C, Mustafa G, Bowe C, Kocsis J. Nodal spacing along regenerated axons following a crush lesion of the developing rat sciatic nerve. Brain Research 1987, 429: 147-54. PMID: 3567658, DOI: 10.1016/0165-3806(87)90148-9.Peer-Reviewed Original ResearchConceptsRat sciatic nerveSciatic nerveRegenerated nervesCrush lesionRegenerated rat sciatic nerveNewborn rat pupsSciatic nerve axonsPostnatal ageRegenerated axonsPostnatal eventsRat pupsNerveNerve axonsMyelin sheathL increaseAxonsWeeksBirthAgeLesionsMyelinationSignsRemodellingSuch signsLength growth