1993
The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve
Lim J, Utzschneider D, Sakatani K, Kocsis J. The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve. Brain Research 1993, 72: 15-20. PMID: 8384095, DOI: 10.1016/0165-3806(93)90155-4.Peer-Reviewed Original ResearchConceptsOptic nerveRat optic nerveEffect of GABAMD ratsNipecotic acidGABA sensitivityGABA uptake inhibitor nipecotic acidNormal optic nervesGABAA receptor agonistOptic nerve axonsEarly postnatal periodCentral nervous system axonsThird postnatal weekSucrose gap techniqueResult of myelinationLarger GABAAxonal excitabilityControl ratsGABAA receptorsEndogenous releasePostnatal periodPostnatal weekNerve sensitivityNerveGABA
1988
Diminished dorsal root GABA sensitivity following chronic peripheral nerve injury
Kingery W, Fields R, Kocsis J. Diminished dorsal root GABA sensitivity following chronic peripheral nerve injury. Experimental Neurology 1988, 100: 478-490. PMID: 3366201, DOI: 10.1016/0014-4886(88)90033-7.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidPrimary afferent depolarizationDorsal rootsGABA sensitivityNerve lesionsSciatic nerveDorsal root compound action potentialsChronic peripheral nerve injurySciatic crush injurySciatic nerve lesionChronic pain syndromeLumbar dorsal rootsPeripheral nerve injuryPeripheral nerve lesionsPeripheral nerve transectionSucrose gap chamberCompound action potentialDorsal root fibersRat lumbar dorsal rootsDorsal root axotomyPain syndromeNerve injuryCrush injuryNerve transectionSciatic axotomy