2000
Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons
Everill B, Kocsis J. Nerve growth factor maintains potassium conductance after nerve injury in adult cutaneous afferent dorsal root ganglion neurons. Neuroscience 2000, 100: 417-422. PMID: 11008179, PMCID: PMC2605351, DOI: 10.1016/s0306-4522(00)00263-3.Peer-Reviewed Original ResearchConceptsTransient A-currentNerve growth factorDorsal root ganglion neuronsK currentsNerve ligationGrowth factorA-currentGanglion neuronsSciatic nerveWhole-cell patch-clamp techniquePotassium conductanceDistal nerve segmentsAfferent cell bodiesMini-osmotic pumpsVoltage-dependent potassium conductancePatch-clamp techniqueTransient potassium currentAppropriate ion replacementNerve growth factor treatmentGrowth factor treatmentNerve injuryNerve crushNerve segmentsCutaneous afferentsControl neurons
1999
Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy
Everill B, Kocsis J. Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy. Journal Of Neurophysiology 1999, 82: 700-708. PMID: 10444667, DOI: 10.1152/jn.1999.82.2.700.Peer-Reviewed Original ResearchConceptsDorsal root ganglion neuronsCutaneous afferent neuronsAfferent neuronsGanglion neuronsPotassium currentWhole-cell patch-clamp recordingsCell patch-clamp recordingsPrimary afferent neuronsEffects of axotomyPatch-clamp recordingsControl cellsAppropriate ion replacementAcute ligationNerve ligationDRG neuronsExcitability changesChannel blockersNeuronal excitabilityPharmacological componentsAxotomyNeuronsLigationBasis of sensitivityCellsBlockers