2002
Consequences and Determinants of Adherence to Antiretroviral Medication: Results from Adult Aids Clinical Trials Group Protocol 370
Ickovics J, Cameron A, Zackin R, Bassett R, Chesney M, Johnson VA, Kuritzkes DR, Acosta E, Barnett R, Bell D, Cannmann S, Eron J, Fischl M, Marschner I, Martinez A, Morse G, Pettinelli C, Sommadossi J, Wood K, Murphy R, Priller N, Sha B, French N, van der Horst C, Marcus C, Lane T, Horton J, Schooley R, Putnam B, Shugarts D, Johnson S, Fife K, Black J, Heise D, Todd K, Bagur J, Vazquez G, Lopez I, Ramirez V, Hill R, Wright S, McCulloch B, Saag M, Slamowitz D, Cain P, Merigan T, Tallman V, Greisberger C, Shoemaker M, Lewis M, Hewitt R, Havlir D, Nuffer K, Wininger D, Watson S, Clark J, Jackson C, Rodriguez A, Scerpella E, Tebas P, Stiffler T, Royal M, Powderly W, Collier A, Storey S, Houseworth L, Conley N, Lederman M, Kalayjian B, Ingersol K, McVey R, Gluckman S, Helker C, Kappes R, Kim D, Albrecht M, Koziol C, Govan; T, Miles S, Chafey S, Mitsuyasu R, Sacks H, Mildvan D, Shikuma C, Millard M, Souza S. Consequences and Determinants of Adherence to Antiretroviral Medication: Results from Adult Aids Clinical Trials Group Protocol 370. Antiviral Therapy 2002, 7: 185-193. PMID: 12487386, DOI: 10.1177/135965350200700308.Peer-Reviewed Original ResearchConceptsPlasma HIV-1 RNA levelsHIV-1 RNA levelsCD4 cell countWeek 24Adherence ratesClinical trialsBaseline plasma HIV-1 RNA levelsAdult AIDS Clinical Trials GroupCell countAIDS Clinical Trials GroupRNA levelsAIDS clinical trialsAdverse clinical eventsAssociation of adherenceOverall adherence rateDeterminants of adherenceClinical Trials GroupSelf-reported adherencePredictors of adherencePatterns of adherenceNon-nucleoside reversePotential confounding variablesVirological outcomesAntiretroviral therapyAdverse events
1999
Recruitment in AIDS Clinical Trials: Investigation of Sociodemographic and Psychosocial Factors Affecting Participation in Clinical Research
Ethier K, Rodriguez M, Fox-Tierney R, Martin C, Friedland G, Ickovics J. Recruitment in AIDS Clinical Trials: Investigation of Sociodemographic and Psychosocial Factors Affecting Participation in Clinical Research. AIDS And Behavior 1999, 3: 219-230. DOI: 10.1023/a:1025456527845.Peer-Reviewed Original ResearchTrial participantsIDU historyClinical trialsAIDS clinical trialsGroup of HIVTrial regimenMedical therapyPsychosocial factorsHIV therapeuticsClinical researchTrial resultsTrialsBehavioral factorsHIVSociodemographic dimensionsPrimary objectiveParticipantsNonparticipantsRegimenPatientsTherapyMSMSociodemographicsRecruitment
1997
Adherence in AIDS clinical trials: A framework for clinical research and clinical care
Ickovics J, Meisler A. Adherence in AIDS clinical trials: A framework for clinical research and clinical care. Journal Of Clinical Epidemiology 1997, 50: 385-391. PMID: 9179096, DOI: 10.1016/s0895-4356(97)00041-3.Peer-Reviewed Original ResearchConceptsClinical trialsAIDS clinical trialsPoor medication adherenceAssessment of adherencePatient-provider relationshipClinical trial dataProtease inhibitor drugsTreatment regimenMedication adherenceMedical adherencePatient participationClinical careDrug failureTherapeutic outcomesViral resistanceNew treatmentsPatient careTrial dataTherapeutic valueClinical settingClinical interventionsClinical researchInhibitor drugsTrialsGood adherence