2013
Ascl1/Mash1 Promotes Brain Oligodendrogenesis during Myelination and Remyelination
Nakatani H, Martin E, Hassani H, Clavairoly A, Maire CL, Viadieu A, Kerninon C, Delmasure A, Frah M, Weber M, Nakafuku M, Zalc B, Thomas JL, Guillemot F, Nait-Oumesmar B, Parras C. Ascl1/Mash1 Promotes Brain Oligodendrogenesis during Myelination and Remyelination. Journal Of Neuroscience 2013, 33: 9752-9768. PMID: 23739972, PMCID: PMC3892435, DOI: 10.1523/jneurosci.0805-13.2013.Peer-Reviewed Original ResearchConceptsOligodendrocyte precursor cellsNeonatal periodCortical oligodendrocyte precursor cellsOligodendrocyte developmentCortical subventricular zoneSubventricular zone progenitorsMultiple sclerosis lesionsMyelin-forming cellsPostnatal cortexRemyelination processFocal demyelinationCorpus callosumSubventricular zoneOPC differentiationPostnatal brainMouse modelAscl1 functionOligodendrogenesisOPC developmentSclerosis lesionsASCL1 expressionCortical progenitorsRemyelinationProneural transcription factorsOligodendrocytes
2012
Live Imaging of Targeted Cell Ablation in Xenopus: A New Model to Study Demyelination and Repair
Kaya F, Mannioui A, Chesneau A, Sekizar S, Maillard E, Ballagny C, Houel-Renault L, DuPasquier D, Bronchain O, Holtzmann I, Desmazieres A, Thomas JL, Demeneix BA, Brophy PJ, Zalc B, Mazabraud A. Live Imaging of Targeted Cell Ablation in Xenopus: A New Model to Study Demyelination and Repair. Journal Of Neuroscience 2012, 32: 12885-12895. PMID: 22973012, PMCID: PMC3460536, DOI: 10.1523/jneurosci.2252-12.2012.Peer-Reviewed Original ResearchConceptsDemyelination/remyelination processesProcess of demyelinationAxonal damageRemyelination processMyelin repairOligodendrocyte ablationMTZ treatmentTwo-photon imagingVivo modelTargeted cell ablationMetronidazoleTherapeutic agentsConditional ablationRetinoic acidOligodendrocytesDemyelinationRemyelination